Brown R G, MacCarthy B, Jahanshahi M, Marsden C D
University Department of Neurology, Institute of Psychiatry, London, England.
Arch Neurol. 1989 Sep;46(9):955-9. doi: 10.1001/archneur.1989.00520450025014.
For the patient, the most important aspect of parkinsonism is the degree to which the disease interferes with daily living. The patient's self-report may be the only way in which such information can be obtained. Depression and cognitive impairment, however, may influence that self-report. In the present study, three ratings of disability, from the patient, a relative, and an independent observer, showed high levels of agreement. The patients' cognitive function made a small but significant contribution to the accuracy of their self-report judged against the relative's rating. Depression, however, played no role. Agreement between patients and relatives for individual items on the disability questionnaire was reasonably high. The results suggest that patients with parkinsonism can provide accurate self-report of their level of disability, even in the presence of depression and cognitive impairment.
对于患者而言，帕金森症最重要的方面是该疾病对日常生活的干扰程度。患者的自我报告可能是获取此类信息的唯一途径。然而，抑郁和认知障碍可能会影响这种自我报告。在本研究中，患者、亲属和独立观察者对残疾程度的三项评分显示出高度一致性。与亲属的评分相比，患者的认知功能对其自我报告的准确性有微小但显著的影响。然而，抑郁并未起到作用。患者与亲属在残疾问卷上各项目的一致性相当高。结果表明，即使存在抑郁和认知障碍，帕金森症患者仍能准确自我报告其残疾程度。
