Ameli F M, Stein M, Provan J L, St Louis E L, Legrand L
Division of Vascular Surgery, Wellesley Hospital, University of Toronto, Ontario, Canada.
Ann Vasc Surg. 1989 Jul;3(3):244-7. doi: 10.1016/S0890-5096(07)60032-6.
This paper presents the results of a retrospective study of 110 percutaneous transluminal angioplasties done over a period of two years on 110 consecutive patients. Anticoagulation or antiplatelet drugs were not used during or after percutaneous transluminal angioplasty. Life-table analysis was used to calculate success rates at one and three months following the procedure. Success rates were determined using three criteria: clinical improvement, pre- and post-percutaneous transluminal angioplasty Doppler studies, and radiographic appearance. Claudication was present in 87 (79%) patients and severe ischemia in 23 (21%) patients. Sixty-eight (62%) PCTAs were done in the iliac arteries, 35 (32%) in the femoral arteries, and 7 (6%) in the popliteal artery. The majority of patients (61%) had 50%-75% arterial stenosis and only 18% had complete occlusion. Percutaneous transluminal angioplasty in the iliac arteries had the best results with cumulative success rates of 90% and 85% at one and three months, respectively. Success rates in the femoral arteries were 83% and 79% and in the popliteal artery 71% and 57% at one and three months, respectively. None of our patients required amputation. Ten patients (9.1%) suffered the following complications within 30 days of percutaneous transluminal angioplasty: death (2), thrombosis (2), perforation (3), minor hematoma (2), and false aneurysm (1). In conclusion, we have shown that percutaneous transluminal angioplasty can be performed safely and effectively without the use of anticoagulation and its associated risks.
本文介绍了一项回顾性研究的结果，该研究对连续110例患者在两年时间内进行的110次经皮腔内血管成形术进行了分析。在经皮腔内血管成形术期间及术后未使用抗凝或抗血小板药物。采用寿命表分析来计算术后1个月和3个月的成功率。成功率根据以下三个标准确定：临床改善情况、经皮腔内血管成形术前及术后的多普勒研究结果以及影像学表现。87例（79%）患者有间歇性跛行，23例（21%）患者有严重缺血。68例（62%）经皮腔内血管成形术在髂动脉进行，35例（32%）在股动脉进行，7例（6%）在腘动脉进行。大多数患者（61%）有50%-75%的动脉狭窄，只有18%的患者完全闭塞。髂动脉经皮腔内血管成形术效果最佳，1个月和3个月时的累积成功率分别为90%和85%。股动脉1个月和3个月时的成功率分别为83%和79%，腘动脉分别为71%和57%。我们的患者均无需截肢。10例患者（9.1%）在经皮腔内血管成形术后30天内出现以下并发症：死亡（2例）、血栓形成（2例）、穿孔（3例）、小血肿（2例）和假性动脉瘤（1例）。总之，我们已经表明，在不使用抗凝药物及其相关风险的情况下，经皮腔内血管成形术可以安全有效地进行。
