Ray Ritwika, Jana Rahul Dev, Bhadra Mayukh, Maiti Debabrata, Lahiri Goutam Kumar
Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai, 400 076 (India).
Chemistry. 2014 Nov 17;20(47):15618-24. doi: 10.1002/chem.201403786. Epub 2014 Oct 3.
The present article describes novel oxidative protocols for direct esterification of alcohols. The protocols involve successful demonstrations of both "cross" and "self" esterification of a wide variety of alcohols. The cross-esterification proceeds under a simple transition-metal-free condition, containing catalytic amounts of TEMPO (2,2,6,6-tetramethyl-1-piperidinyloxy)/TBAB (tetra-n-butylammonium bromide) in combination with oxone (potassium peroxo monosulfate) as the oxidant, whereas the self-esterification is achieved through simple induction of Fe(OAc)2 /dipic (dipic=2,6-pyridinedicarboxylic acid) as the active catalyst under an identical oxidizing environment.
本文描述了用于醇直接酯化的新型氧化方法。这些方法成功展示了多种醇的“交叉”和“自身”酯化反应。交叉酯化反应在简单的无过渡金属条件下进行，该条件包含催化量的TEMPO（2,2,6,6-四甲基-1-哌啶氧基）/TBAB（四正丁基溴化铵），并以过一硫酸钾（oxone）作为氧化剂，而自身酯化反应是在相同的氧化环境下，通过简单引入Fe(OAc)₂ /dipic（dipic = 2,6-吡啶二甲酸）作为活性催化剂来实现的。
