高效、有机催化的有氧醇氧化。
Highly efficient, organocatalytic aerobic alcohol oxidation.
机构信息
Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aobayama 6-3, Sendai 980-8578, Japan.
出版信息
J Am Chem Soc. 2011 May 4;133(17):6497-500. doi: 10.1021/ja110940c. Epub 2011 Apr 7.
5-Fluoro-2-azaadamantane N-oxyl (5-F-AZADO) realizes a simple, organocatalytic aerobic alcohol oxidation system that has a wide scope under mild conditions at ambient pressure and temperature and is weakly acidic and halogen- and transition-metal-free. The oxoammonium nitrate (5-F-AZADO(+)NO(3)(-)) works as a bifunctional catalyst of 5-F-AZADO and NO(x) that enables the catalytic aerobic oxidation of alcohols by itself (a metal-salt-free system).
5-氟-2-氮杂金刚烷 N-氧自由基（5-F-AZADO）实现了一个简单的、有机催化的有氧醇氧化体系，在温和条件下、环境压力和温度下具有广泛的应用范围，且体系呈弱酸性，不含卤素和过渡金属。过氧硝基金属盐（5-F-AZADO(+)NO(3)(-））作为 5-F-AZADO 和 NO(x)的双功能催化剂，能够自身（无金属盐体系）催化有氧氧化醇。
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