Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Pediatr Blood Cancer. 2015 Mar;62(3):531-2. doi: 10.1002/pbc.25252. Epub 2014 Oct 4.
Treatment of vaginal rhabdomyosarcoma (RMS) with conservative approaches is presently the standard of care. Intravaginal high-dose rate brachytherapy is a very effective treatment while sparing the normal tissue to preserve growth, fertility and prevent organ dysfunction. In this report, we describe the management of an infant with Stage I vaginal RMS, treated with chemotherapy, maximal safe resection and intravaginal brachytherapy using a customized mold and MRI and CT-based three-dimensional (3D) conformal planning, followed by a critical review of the literature.
目前，采用保守方法治疗阴道横纹肌肉瘤（RMS）是标准的治疗方法。阴道内高剂量率近距离放疗是一种非常有效的治疗方法，同时可以保护正常组织，以维持生长、生育能力并预防器官功能障碍。在本报告中，我们描述了一名婴儿的治疗方法，该婴儿患有 I 期阴道 RMS，采用化疗、最大安全切除和使用定制模具以及 MRI 和 CT 三维（3D）适形计划的阴道内近距离放疗，然后对文献进行了批判性回顾。
