Sachok V V, Mokhort M A
Lik Sprava. 2014 Mar-Apr(3-4):109-13.
Presented are experimental data on the influence of calcium antagonists of the third-generation derivatives of 1,4-dihydropyridines--amlodipine (1.5 mg/kg), dimeodipine (1.5 mg/kg)--on parameters of carbohydrate metabolism in rat blood model doxorubicin-induced cardiomyopathy. The possibility for correcting carbohydrate metabolic disorders in the blood with the above drugs through a reduction of lactate, lactate/pyruvic retio, LDH activity, normalization of the level of glycogen, glucose, pyruvate.
呈现了关于第三代1,4 - 二氢吡啶衍生物钙拮抗剂——氨氯地平（1.5毫克/千克）、地莫地平（1.5毫克/千克）对大鼠阿霉素诱导的心肌病血液模型中碳水化合物代谢参数影响的实验数据。通过降低乳酸、乳酸/丙酮酸比值、乳酸脱氢酶活性以及使糖原、葡萄糖、丙酮酸水平正常化，上述药物纠正血液中碳水化合物代谢紊乱的可能性。
