Tsur Abraham, Machtinger Ronit, Segal-Lieberman Gabriella, Orvieto R
Harefuah. 2014 Aug;153(8):478-81, 497, 496.
Obesity is an increasingly widespread health problem. In addition to comorbidities such as diabetes, hypertension, dyslipidemia and cardiovascular disease, obesity has a significant impact on reproductive life, including infertility, miscarriages and high prevalence of pregnancy complications. The present review describes the possible benefits of bariatric surgery regarding fertility and pregnancy outcome. It is well established that bariatric surgery leads to regular ovulatory cycles and improves spontaneous conception rates in obese women. While pregnancy after bariatric surgery is safe and associated with reduced pregnancy complications, pregnant women following bariatric surgery are still at high risk for preterm births and small dimensions of gestational age offsprings. The optimal interval that should be kept between surgery and subsequent pregnancy is controversial, with recent studies emphasizing the importance of nutritional balance rather than the time from surgery to conception as being the most important determinant. Strict peri-conceptional surveillance is mandatory in order to prevent nutritional deficiencies and for the early diagnosis of abnormal fetal growth.
肥胖是一个日益普遍的健康问题。除了糖尿病、高血压、血脂异常和心血管疾病等合并症外，肥胖对生殖生活有重大影响，包括不孕、流产和妊娠并发症的高发生率。本综述描述了减肥手术对生育能力和妊娠结局的潜在益处。众所周知，减肥手术可使肥胖女性的排卵周期规律，并提高自然受孕率。虽然减肥手术后怀孕是安全的，且与妊娠并发症减少相关，但接受减肥手术后的孕妇仍有早产和低出生体重儿的高风险。手术与随后怀孕之间应保持的最佳间隔存在争议，最近的研究强调营养平衡的重要性，而非手术至受孕的时间是最重要的决定因素。为了预防营养缺乏和早期诊断胎儿生长异常，严格的受孕前监测是必不可少的。
