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减重手术与妊娠:神奇的解决方案?

Bariatric surgery and pregnancy: the magical solution?

机构信息

Faculty of Health Sciences, Department of Obstetrics andGynecology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

J Perinat Med. 2013 Mar;41(2):133-40. doi: 10.1515/jpm-2012-0237.

DOI:10.1515/jpm-2012-0237
PMID:23241580
Abstract

The obesity epidemic is a problem of global importance with a profound impact on maternal-fetal health. Currently, 1 in 5 women, worldwide, are obese at time of conception. Normalizing pregravid weight may significantly reduce obstetrical complications and alter the long-term weight status of mother and child. Bariatric surgery is the most efficient form of weight loss in severely obese women. Surgery has the exciting potential to treat obesity in women of reproductive age and to prevent obesity-related reproductive complications. Pregnancy after bariatric surgery appears to be safe and is effective in reducing complications such as gestational diabetes mellitus, gestational hypertensive disorders and fetal macrosomia, but may result in an increase in neonates born small-for-gestational-age.

摘要

肥胖症是一个具有全球重要性的问题,对母婴健康有着深远的影响。目前,全球每 5 名女性中就有 1 人在受孕时肥胖。使孕前体重正常化可能会显著减少产科并发症,并改变母婴的长期体重状况。减重手术是严重肥胖女性最有效的减肥形式。手术有令人兴奋的潜力,可以治疗育龄妇女的肥胖症,并预防肥胖相关的生殖并发症。肥胖症患者接受减重手术后妊娠似乎是安全的,并且可以有效减少妊娠糖尿病、妊娠高血压疾病和胎儿巨大儿等并发症,但可能导致新生儿出生体重小于胎龄的比例增加。

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1
Bariatric surgery and pregnancy: the magical solution?减重手术与妊娠:神奇的解决方案?
J Perinat Med. 2013 Mar;41(2):133-40. doi: 10.1515/jpm-2012-0237.
2
Pregnancy and neonatal outcome after bariatric surgery.肥胖症患者接受减重手术后的妊娠与新生儿结局。
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Pregnancy outcomes after bariatric surgery: maternal, fetal, and infant implications.减肥手术后的妊娠结局:对母体、胎儿和婴儿的影响
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Impact of prior bariatric surgery on maternal and fetal outcomes among obese and non-obese mothers.肥胖和非肥胖母亲中既往减重手术对母婴结局的影响。
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Pregnancy after bariatric surgery--a review of benefits and risks.肥胖症手术后的妊娠——获益与风险的综述。
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The risk of adverse pregnancy outcome after bariatric surgery: a nationwide register-based matched cohort study.减重手术后不良妊娠结局的风险:一项全国范围内基于登记的匹配队列研究。
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引用本文的文献

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Maternal Bariatric Surgery and Offspring Health: A Sibling Matched Analysis Comparing Offspring Born before and after the Surgery.母亲肥胖症手术与后代健康:一项同胞匹配分析,比较手术前后出生的后代情况。
J Clin Med. 2023 Apr 23;12(9):3056. doi: 10.3390/jcm12093056.
2
Maternal obesity alters C19MC microRNAs expression profile in fetal umbilical cord blood.孕妇肥胖会改变胎儿脐带血中C19MC微小RNA的表达谱。
Nutr Metab (Lond). 2020 Jul 6;17:52. doi: 10.1186/s12986-020-00475-7. eCollection 2020.
3
Physical Exercise following bariatric surgery in women with Morbid obesity: Study protocol clinical trial (SPIRIT compliant).
病态肥胖女性减肥手术后的体育锻炼:研究方案临床试验(符合SPIRIT标准)
Medicine (Baltimore). 2020 Mar;99(12):e19427. doi: 10.1097/MD.0000000000019427.
4
Targeting the postpartum period to promote weight loss: a systematic review and meta-analysis.针对产后阶段以促进减肥:系统评价和荟萃分析。
Nutr Rev. 2018 Aug 1;76(8):639-654. doi: 10.1093/nutrit/nuy024.
5
Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management.肥胖管理工作组的实用建议肥胖协会对肥胖症的研究后的医疗管理后的肥胖症的医疗管理。
Obes Facts. 2017;10(6):597-632. doi: 10.1159/000481825. Epub 2017 Dec 6.
6
Does Bariatric Surgery Improve Assisted Reproductive Technology Outcomes in Obese Infertile Women?减肥手术能否改善肥胖不孕女性的辅助生殖技术治疗效果?
Obes Surg. 2017 Aug;27(8):2106-2112. doi: 10.1007/s11695-017-2614-9.
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Characterization of visceral and subcutaneous adipose tissue transcriptome in pregnant women with and without spontaneous labor at term: implication of alternative splicing in the metabolic adaptations of adipose tissue to parturition.足月自然分娩和未自然分娩孕妇内脏及皮下脂肪组织转录组特征:可变剪接在脂肪组织对分娩代谢适应中的作用
J Perinat Med. 2016 Oct 1;44(7):813-835. doi: 10.1515/jpm-2015-0259.
8
Bariatric Surgery and the Pregnancy Complicated by Gestational Diabetes.减重手术与并发妊娠期糖尿病的妊娠
Curr Diab Rep. 2016 Apr;16(4):21. doi: 10.1007/s11892-016-0716-8.