Azevedo Da Silva M, Lemogne C, Melchior M, Zins M, Van Der Waerden J, Consoli S M, Goldberg M, Elbaz A, Singh-Manoux A, Nabi H
Centre for Research in Epidemiology and Population Health, Epidemiology of Occupational and Social Determinants of Health, INSERM U1018, Villejuif, France; Université de Versailles St Quentin, Villejuif, France.
Acta Psychiatr Scand. 2015 Apr;131(4):307-17. doi: 10.1111/acps.12341. Epub 2014 Oct 7.
To examine whether non-psychiatric hospitalizations rates were higher in those with mental disorders.
In a cohort of 15,811 employees, aged 35-50 years in 1989, mental disorder status was defined from 1989 to 2000. Hospitalizations for all-causes, myocardial infarction (MI), stroke, and cancer, were recorded yearly from 2001 to 2011. Negative binomial regression models were used to estimate hospitalization rates over the follow-up.
After controlling for baseline sociodemographic factors, health-related behaviors, self-rated health, and self-reported medical conditions, participants with a mental disorder had significantly higher rates of all-cause hospitalization [incidence rate ratio, IRR=1.20 (95%, 1.14-1.26)], as well as hospitalization due to MI [IRR=1.44 (95%, 1.12-1.85)]. For stroke, the IRR did not reach statistical significance [IRR=1.37 (95%, 0.95-1.99)] and there was no association with cancer [IRR=1.01 (95%, 0.86-1.19)]. A similar trend was observed when mental disorders groups were considered (no mental disorder, depressive disorder, mental disorders due to psychoactive substance use, other mental disorders, mixed mental disorders, and severe mental disorder).
In this prospective cohort of employees with stable employment as well as universal access to healthcare, we found participants with mental disorders to have higher rates of non-psychiatric hospitalizations.
研究患有精神障碍的人群非精神科住院率是否更高。
在一个由1989年年龄在35至50岁之间的15811名员工组成的队列中，从1989年至2000年确定精神障碍状况。从2001年至2011年每年记录全因住院、心肌梗死（MI）、中风和癌症的住院情况。使用负二项回归模型估计随访期间的住院率。
在控制了基线社会人口学因素、健康相关行为、自我评估健康状况和自我报告的医疗状况后，患有精神障碍的参与者全因住院率显著更高[发病率比，IRR = 1.20（95%，1.14 - 1.26）]，以及因MI住院率[IRR = 1.44（95%，1.12 - 1.85）]。对于中风，IRR未达到统计学显著性[IRR = 1.37（95%，0.95 - 1.99）]，且与癌症无关联[IRR = 1.01（95%，0.86 - 1.19）]。当考虑精神障碍组（无精神障碍、抑郁症、精神活性物质所致精神障碍、其他精神障碍、混合性精神障碍和重度精神障碍）时，观察到类似趋势。
在这个就业稳定且普遍享有医疗保健的前瞻性员工队列中，我们发现患有精神障碍的参与者非精神科住院率更高。
