The Hebrew University of Jerusalem , Jerusalem , Israel.
Department for the Treatment of Substance Abuse, Ministry of Health , The Hebrew University of Jerusalem, Jerusalem , Israel.
J Dual Diagn. 2019 Jul-Sep;15(3):130-139. doi: 10.1080/15504263.2019.1609149. Epub 2019 May 12.
A significant proportion of patients with severe mental illness also experience substance use disorder. For these dual diagnosis (DD) patients, treatment is more complicated and prognosis is worse. Despite the introduction of the Community Rehabilitation of Persons With Mental Health Disability Law in 2000 and ongoing national mental health reforms, psychiatric services in Israel are not meeting the needs of an increasing number of DD patients. This study examines, for the first time in Israel, the prevalence of DD and patterns of psychiatric hospitalizations of chronic psychotic disorder patients with and without substance use disorder. The National Psychiatric Case Registry provided data on 18,684 persons with schizophrenia/schizoaffective disorders, aged 18-65, with a psychiatric hospitalization during the period 1963-2016 (with at least one hospitalization in 2010-15). Patients were considered as having DD if their substance use disorder was indicated in at least two, or 20%, of hospitalizations. Regression modeling predicted hospitalization measures (number of hospitalizations, total days hospitalized, length of stay). Results were also analyzed by legal status of admission (voluntary or involuntary; psychiatrist-ordered and court-ordered). One-third of patients with chronic psychotic disorder met DD criteria, with a threefold higher rate among males (37.1%) than females (12.8%). Particularly high rates of DD (nearly 50%) were noted among male immigrants from Ethiopia. Compared with non-substance use disorder patients, DD patients had a significantly younger mean age at first hospitalization and shorter average length of stay per hospitalization but a greater number of hospitalizations and total hospital days ( < .0001 for all comparisons). The associations between DD status and hospitalization characteristics remained significant even after accounting for the effects of confounding factors. Hospitalization characteristics were also associated significantly with sex, population group, age, age at first hospitalization, and country of origin. The rate of court-ordered observation or hospitalization was threefold higher in the DD group. : These findings, which broadly align with other countries, reflect a scarcity of outpatient services for DD patients with schizophrenia/schizoaffective disorder and substance use disorder. To achieve long-term mental health improvements, an expansion of community-based integrative treatment and rehabilitation services is needed in Israel.
相当比例的严重精神疾病患者也同时患有物质使用障碍。对于这些双重诊断(DD)患者来说,治疗更加复杂,预后更差。尽管 2000 年出台了《精神卫生残疾者社区康复法》,国家也在不断进行精神卫生改革,但以色列的精神科服务仍无法满足日益增多的 DD 患者的需求。本研究首次在以色列调查了 DD 的流行程度,以及患有和不患有物质使用障碍的慢性精神病患者的住院模式。国家精神病案例登记处提供了 1963 年至 2016 年期间(2010-15 年至少有一次住院治疗)18684 名年龄在 18-65 岁之间的精神分裂症/分裂情感障碍患者的住院数据。如果患者的物质使用障碍在至少两次住院中(或 20%)被记录,则认为他们患有 DD。回归模型预测了住院治疗措施(住院次数、住院总天数、住院时间)。研究结果还按入院的法律地位(自愿或非自愿;精神病医生指令和法院指令)进行了分析。三分之一的慢性精神病患者符合 DD 标准,男性(37.1%)的发病率是女性(12.8%)的三倍。来自埃塞俄比亚的男性移民的 DD 发病率特别高(近 50%)。与非物质使用障碍患者相比,DD 患者的首次住院年龄明显更小,每次住院的平均住院时间更短,但住院次数和总住院天数更多(所有比较均 < 0.0001)。即使考虑到混杂因素的影响,DD 状态与住院特征之间的关联仍然显著。住院特征也与性别、人群组、年龄、首次住院年龄和原籍国显著相关。DD 组的法院指令观察或住院的比例是对照组的三倍。这些发现与其他国家基本一致,反映了以色列为患有精神分裂症/分裂情感障碍和物质使用障碍的 DD 患者提供的门诊服务严重不足。为了实现长期的精神健康改善,以色列需要扩大基于社区的综合治疗和康复服务。