双侧后巩膜炎作为IgA肾病的首发表现：病例报告及文献复习
Bilateral Posterior Scleritis Presenting as the First Manifestation of Immunoglobulin A Nephropathy: Case Report and Review of the Literature.
作者信息
Yan Yan, Zhang Qiong
机构信息
a Department of Ophthalmology , Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China.
出版信息
Ocul Immunol Inflamm. 2016;24(1):43-8. doi: 10.3109/09273948.2014.964420. Epub 2014 Oct 7.
PURPOSE
We describe a case of posterior scleritis presenting as the first manifestation in a Chinese patient with immunoglobin A nephropathy (IgAN).
METHODS
Retrospective review of our patient and review of the published case reports from PubMed search.
RESULTS
A 43-year-old woman developed bilateral posterior scleritis. Microscopic hematuria and proteinuria was found by urinalysis, and a kidney biopsy revealed IgAN. The posterior scleritis was resolved with oral prednisolone. For the review, 12 cases of episcleritis (70.6%), 4 cases of scleritis (23.5%), and 1 case of posterior scleritis (5.9%) associated with IgAN were analyzed. Five patients (29.4%) had scleritis or episcleritis as the first presenting manifestation.
CONCLUSIONS
Posterior scleritis may be the first manifestation of IgAN in a patient. For any adult patient with scleral/episcleral inflammation, urinalysis should be done to rule out IgAN.
目的
我们描述了一例在中国患有免疫球蛋白A肾病（IgAN）的患者中，后巩膜炎作为首发表现的病例。
方法
对我们的患者进行回顾性分析，并通过PubMed检索已发表的病例报告。
结果
一名43岁女性出现双侧后巩膜炎。尿液分析发现镜下血尿和蛋白尿，肾脏活检显示为IgAN。口服泼尼松龙后后巩膜炎得到缓解。在回顾中，分析了12例与IgAN相关的表层巩膜炎（70.6%）、4例巩膜炎（23.5%）和1例后巩膜炎（5.9%）。5名患者（29.4%）以巩膜炎或表层巩膜炎作为首发表现。
结论
后巩膜炎可能是IgAN患者的首发表现。对于任何患有巩膜/表层巩膜炎症的成年患者，都应进行尿液分析以排除IgAN。
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