Department of Nephrology, NU Hospitals, Bengaluru, Karnataka, India.
Saudi J Kidney Dis Transpl. 2021 Nov-Dec;32(6):1790-1794. doi: 10.4103/1319-2442.352442.
Immunoglobulin A (IgA) nephropathy is usually restricted to the kidneys in most cases, but associations with other immune and inflammatory diseases exist. Scleritis, however, is an unusual association. We present an observational case series of two patients who initially presented with recurrent episodes of scleritis. A thorough evaluation for recurrent scleritis did not reveal any secondary cause per se. They were further evaluated extensively for incidental proteinuria and microscopic hematuria. Renal function was normal. Renal biopsy was performed which revealed IgA nephropathy in both the patients. They were given oral prednisolone and telmisartan for six months and followed for nine and six months, respectively, after steroids were discontinued. Proteinuria remitted, renal function remained normal, and there were no further episodes of scleritis in these patients.
免疫球蛋白 A (IgA) 肾病通常在大多数情况下仅局限于肾脏，但与其他免疫和炎症性疾病有关。然而，巩膜炎是一种不常见的关联。我们报告了两例最初表现为复发性巩膜炎的患者的观察性病例系列。对复发性巩膜炎的彻底评估本身并没有发现任何继发性病因。他们进一步广泛评估了偶发性蛋白尿和镜下血尿。肾功能正常。进行了肾活检，结果显示两例患者均患有 IgA 肾病。他们接受了口服泼尼松龙和替米沙坦治疗六个月，并在停用类固醇后分别随访了九个月和六个月。蛋白尿缓解，肾功能保持正常，这些患者也没有出现进一步的巩膜炎发作。
