Esparza N, Díez J
Servicio de Nefrología, Clínica Universitaria, Universidad de Navarra, Spain.
Eur J Pharmacol. 1989 Jul 18;166(2):349-52. doi: 10.1016/0014-2999(89)90082-4.
Ouabain- and bumetanide-resistant potassium fluxes were measured in human erythrocytes incubated in a medium containing calcium and a calcium ionophore. Pharmacological concentrations of rat atrial natriuretic peptide stimulated these fluxes. Although human erythrocytes lack atrial natriuretic peptide receptors, our results suggest that the hormone can modify transmembrane K+ movements.
在含有钙和钙离子载体的培养基中孵育的人红细胞中,测量了哇巴因和布美他尼抗性钾通量。大鼠心房利钠肽的药理浓度刺激了这些通量。尽管人红细胞缺乏心房利钠肽受体,但我们的结果表明,该激素可改变跨膜钾离子运动。