Ismaĭlova I M, Berdinskikh N K
Fiziol Zh (1978). 1989 Jul-Aug;35(4):91-4.
The influence of ceruloplasmin on the development of delayed hypersensitivity (DHS) and activity of T-suppressors were studied in experiments on intact Balb/c mice. Ceruloplasmin introduced in a dose of 5 mg per 1 kg of weight a day before immunization of animals is shown to have a stimulating effect. The amount of the introduced drug being raised to 200 mg per 1 kg of weight suppressed the ability of organism to form DHS effect rather than increased it. Ceruloplasmin is stated to inhibit induction of DHS suppressors and to exert no effect on the expression of functional activity of the formed suppressors.
在对健康的Balb/c小鼠进行的实验中，研究了铜蓝蛋白对迟发型超敏反应（DHS）发展和T抑制细胞活性的影响。在动物免疫前一天，以每1千克体重5毫克的剂量注射铜蓝蛋白，显示出具有刺激作用。将注射药物的量增加到每1千克体重200毫克时，会抑制机体形成DHS效应的能力，而不是增强该能力。据称，铜蓝蛋白会抑制DHS抑制细胞的诱导，并且对已形成的抑制细胞的功能活性表达没有影响。
