Jeppesen Peter, Krag Susanne
Øjenafdelingen, Aarhus Universitetshospital, Nørrebrogade 44, 8000 Aarhus. E-mail:
Ugeskr Laeger. 2014 Aug 25;176(35).
The risk of steroid-induced elevation of intraocular pressure and glaucoma is clinical relevant and require monitoring of patients at risk. The risk depends on route of administration, potency and individual risk factors such as primary open glaucoma (POAG), first-degree relative with POAG, age (children) and myopia. Steroid-induced elevation of intraocular pressure is most commonly associated with ocular application and systemic administration but may occur after periocular cutaneous application and nasal and inhalation therapy in patients with individual risk factors.
类固醇诱导的眼压升高和青光眼风险具有临床相关性,需要对有风险的患者进行监测。该风险取决于给药途径、效力以及个体风险因素,如原发性开角型青光眼(POAG)、POAG的一级亲属、年龄(儿童)和近视。类固醇诱导的眼压升高最常与眼部应用和全身给药有关,但在有个体风险因素的患者中,眼周皮肤应用、鼻腔和吸入治疗后也可能发生。