Nuyen Brenda, Weinreb Robert N, Robbins Shira L
Ratner Children's Eye Center at the Shiley Eye Institute, University of California San Diego, La Jolla, California.
Shiley Eye Institute, University of California San Diego, La Jolla, California.
J AAPOS. 2017 Feb;21(1):1-6. doi: 10.1016/j.jaapos.2016.09.026. Epub 2017 Jan 10.
Steroid medications may cause elevation of intraocular pressure, sometimes with permanent damage to the optic nerve. These therapies, via various routes of administration, are commonly prescribed for children, but the potential sequelae of elevated intraocular pressure and glaucomatous optic nerve damage can be even more severe and devastating in children than in adults. This review discusses the pathophysiology and potential risk factors, including the impact of intraocular pressure elevation via the different common routes of administration of steroids, clinical evaluation, and management of steroid response and steroid-induced glaucoma in children.
类固醇药物可能会导致眼压升高,有时会对视神经造成永久性损伤。这些疗法通过各种给药途径,常用于儿童,但眼压升高和青光眼性视神经损伤的潜在后遗症在儿童中可能比在成人中更为严重和具有破坏性。这篇综述讨论了病理生理学和潜在风险因素,包括通过不同常见类固醇给药途径导致眼压升高的影响、临床评估以及儿童类固醇反应和类固醇性青光眼的管理。