Theódórsdóttir Asta, Blaabjerg Morten, Falah Masoud
Ásta Theódórsdóttir, Neurologisk Afdeling, Odense Universitetshospital, Sdr. Boulevard 29, 5000 Odense C. E-mail:
Ugeskr Laeger. 2014 Aug 25;176(35).
A 41-year-old woman with relapsing-remitting multiple sclerosis came to the outpatient-clinic, prior to a scheduled infusion with natalizumab. She had been treated with natalizumab for four years. Prior to treatment she did not wish to have her John Cunningham virus status tested. At the consultation she appeared disoriented and answered questions inadequately. An MRI was consistent with progressive multifocal leucoencephalopathy, and treatment with plasmapheresis was startet immediatly. The patient deceased four months later.
一名41岁复发缓解型多发性硬化症女性患者，在预定输注那他珠单抗之前前来门诊就诊。她接受那他珠单抗治疗已四年。治疗前她不希望检测约翰·坎宁安病毒状态。会诊时她显得神志不清，回答问题不充分。磁共振成像显示符合进行性多灶性白质脑病，随即开始进行血浆置换治疗。患者四个月后死亡。
