一种基于萘酰亚胺的荧光“开启”探针，用于检测水溶液和活细胞中的Pb(2+)。
A naphthalimide-based fluorescence "turn-on" probe for the detection of Pb(2+) in aqueous solution and living cells.
作者信息
Un Hio-Ieng, Huang Chang-Bo, Huang Junhai, Huang Chusen, Jia Ti, Xu Lin
机构信息
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai (China).
出版信息
Chem Asian J. 2014 Dec;9(12):3397-402. doi: 10.1002/asia.201402946. Epub 2014 Oct 7.
An easily available naphthalimide-based fluorescent probe NPA for Pb(2+) detection was successfully developed. NPA exhibited an obvious fluorescence turn-on response toward Pb(2+) in aqueous solution and in living cells. Moreover, a series of model compounds were rationally designed and synthesized in order to explore the sensing mechanism and binding mode of NPA with Pb(2+) .
一种用于检测Pb(2+)的易于获得的基于萘二甲酰亚胺的荧光探针NPA被成功开发出来。NPA在水溶液和活细胞中对Pb(2+)表现出明显的荧光开启响应。此外，为了探究NPA与Pb(2+)的传感机制和结合模式，还合理设计并合成了一系列模型化合物。
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