Suga Takuya, Mizuno Hajime, Takaya Jun, Iwasawa Nobuharu
Department of Chemistry, Tokyo Institute of Technology, O-okayama, Meguro-ku, Tokyo 152-8551, Japan.
Chem Commun (Camb). 2014 Nov 28;50(92):14360-3. doi: 10.1039/c4cc06188h.
Direct carboxylation of simple arenes under atmospheric pressure of CO2 is achieved through a rhodium-catalyzed C-H bond activation without the assistance of a directing group. Various arenes such as benzene, toluene, xylene, electron-rich or electron-deficient benzene derivatives, and heteroaromatics are directly carboxylated with high TONs.
在无导向基团辅助的情况下，通过铑催化的C-H键活化实现了简单芳烃在二氧化碳大气压下的直接羧基化反应。各种芳烃，如苯、甲苯、二甲苯、富电子或缺电子的苯衍生物以及杂芳烃，都能以高TON值直接进行羧基化反应。
