Benenson E V, Tsaĭ E G, Tabyshalieva A S
Revmatologiia (Mosk). 1989 Apr-Jun(2):45-9.
The authors studied the activity of nuclear chromatin of the peripheral T- and B-lymphocytes in the polyclonal activation test using the method of quantitative cytofluorometry. A new experimental model in vitro has been proposed for the study of regulatory function of T-lymphocytes. It was found out that in approximately 50% of osteoarthrosis patients the greater part of the peripheral lymphoid population is in the state of initial activation and the activated B-lymphocytes occur more frequently than T-lymphocytes.
作者采用定量细胞荧光测定法，在多克隆激活试验中研究了外周T淋巴细胞和B淋巴细胞的核染色质活性。提出了一种体外新实验模型用于研究T淋巴细胞的调节功能。结果发现，在大约50%的骨关节炎患者中，外周淋巴样细胞群的大部分处于初始激活状态，且激活的B淋巴细胞比T淋巴细胞出现得更频繁。
