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[因膀胱肿瘤接受膀胱切除术患者的尿道癌]

[Carcinoma of the urethra in patients having undergone cystectomy for neoplasm of the bladder].

作者信息

Vicini D, Mensi M, Mirando P, Scoppetta F P

出版信息

Arch Ital Urol Nefrol Androl. 1989 Sep;61(3):217-21.

PMID:2529636
Abstract

The multifocality of the cancer of the urethra is a concept already known so for time, therefore urethral lesions are expected in patients with carcinoma of the bladder with an incidence which varies from 4% to 18%. A retrospective study of incidence of transitional cell carcinoma of the urethra of personal sample of patients having cystectomy is reported. Of 259 patients who underwent cystectomy 13 developed a urethral tumour; 7.7% according to the international literature. The paper regards the characteristics of the urethral tumour by defining patients liable to risk where the carcinoma is plurifocal, or situated at the neck of the bladder and where frequent endoscopic operations have been performed or when there is a urethral "ca in situ". In these cases cystourethrectomy is suggested while the urethra is removed in presence of positive cytology in other forms. According to the authors' experience the survival of patients who have undergone a urethrectomy after cystectomy is 46%.

摘要

尿道癌的多灶性是一个早已为人所知的概念,因此,膀胱癌患者中预期会出现尿道病变,其发生率在4%至18%之间。本文报告了一项对接受膀胱切除术患者个人样本中尿道移行细胞癌发病率的回顾性研究。在259例接受膀胱切除术的患者中,有13例发生了尿道肿瘤;根据国际文献,发病率为7.7%。本文通过定义那些患多灶性癌、癌位于膀胱颈部、频繁接受内镜手术或存在尿道“原位癌”的有风险患者,探讨了尿道肿瘤的特征。在这些情况下,建议行膀胱尿道切除术,而在其他情况下,若细胞学检查呈阳性,则切除尿道。根据作者的经验,膀胱切除术后接受尿道切除术的患者生存率为46%。

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