Katsambas A, Antoniou C, Frangouli E, Avgerinou G, Michailidis D, Stratigos J
A. Sygros Hospital for Diseases of the Skin, University of Athens, Greece.
Br J Dermatol. 1989 Sep;121(3):353-7. doi: 10.1111/j.1365-2133.1989.tb01429.x.
Fifty patients with seborrhoeic dermatitis were treated with 2% ketoconazole cream (n = 24) or with 1% hydrocortisone cream (n = 26) for 4 weeks in a double-blind comparative study. These twice daily applications resulted in 87.2% symptomatic improvement for hydrocortisone vs. 81.6% for ketoconazole. The number of P. ovale yeasts was significantly reduced after the application of ketoconazole compared with hydrocortisone. The incidence of side-effects was low in both groups.
在一项双盲对照研究中，50例脂溢性皮炎患者分别使用2%酮康唑乳膏（n = 24）或1%氢化可的松乳膏（n = 26）治疗4周。每天两次涂抹药物后，氢化可的松组症状改善率为87.2%，酮康唑组为81.6%。与氢化可的松相比，使用酮康唑后卵圆形糠秕孢子菌数量显著减少。两组的副作用发生率均较低。
