Kaur Paramjit, Kaur Gagandeep
Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh, India.
Int J Appl Basic Med Res. 2014 Sep;4(Suppl 1):S8-S12. doi: 10.4103/2229-516X.140708.
Dengue fever has emerged as a global public health problem in the recent decades. The clinical spectrum of the disease ranges from dengue fever to dengue hemorrhagic fever and dengue shock syndrome. The disease is characterized by increased capillary permeability, thrombocytopenia and coagulopathy. Thrombocytopenia with hemorrhagic manifestations warrants platelet transfusions. There is lack of evidence-based guidelines for transfusion support in patients with dengue fever. This contributes to inappropriate use of blood components and blood centers constantly face the challenge of inventory management during dengue outbreaks. The current review is aimed to highlight the role of platelets and other blood components in the management of dengue. The review was performed after searching relevant published literature in PubMed, Science Direct, Google scholar and various text books and journal articles.
近几十年来，登革热已成为一个全球公共卫生问题。该疾病的临床谱范围从登革热到登革出血热和登革休克综合征。该疾病的特征是毛细血管通透性增加、血小板减少和凝血病。伴有出血表现的血小板减少症需要输注血小板。对于登革热患者的输血支持，缺乏循证指南。这导致血液成分的不恰当使用，并且在登革热疫情期间，血库一直面临库存管理的挑战。本综述旨在强调血小板和其他血液成分在登革热治疗中的作用。本综述是在检索了PubMed、Science Direct、谷歌学术以及各种教科书和期刊文章中相关的已发表文献之后进行的。
