Beatty Mark E, Beutels Philippe, Meltzer Martin I, Shepard Donald S, Hombach Joachim, Hutubessy Raymond, Dessis Damien, Coudeville Laurent, Dervaux Benoit, Wichmann Ole, Margolis Harold S, Kuritsky Joel N
Pediatric Dengue Vaccine Initiative, International Vaccine Institute, Kwanak-gu, Seoul, Republic of Korea.
Am J Trop Med Hyg. 2011 Mar;84(3):473-88. doi: 10.4269/ajtmh.2011.10-0521.
Dengue vaccines are currently in development and policymakers need appropriate economic studies to determine their potential financial and public health impact. We searched five databases (PubMed, EMBASE, LILAC, EconLit, and WHOLIS) to identify health economics studies of dengue. Forty-three manuscripts were identified that provided primary data: 32 report economic burden of dengue and nine are comparative economic analyses assessing various interventions. The remaining two were a willingness-to-pay study and a policymaker survey. An expert panel reviewed the existing dengue economic literature and recommended future research to fill information gaps. Although dengue is an important vector-borne disease, the economic literature is relatively sparse and results have often been conflicting because of use of inconsistent assumptions. Health economic research specific to dengue is urgently needed to ensure informed decision making on the various options for controlling and preventing this disease.
登革热疫苗目前正在研发中，政策制定者需要进行适当的经济研究，以确定其潜在的财政和公共卫生影响。我们检索了五个数据库（PubMed、EMBASE、LILAC、EconLit和WHOLIS），以查找登革热的卫生经济学研究。共识别出43篇提供原始数据的手稿：32篇报告了登革热的经济负担，9篇是评估各种干预措施的比较经济分析。其余两篇是支付意愿研究和政策制定者调查。一个专家小组审查了现有的登革热经济文献，并建议开展未来研究以填补信息空白。尽管登革热是一种重要的媒介传播疾病，但经济文献相对较少，而且由于假设不一致，结果往往相互矛盾。迫切需要开展针对登革热的卫生经济研究，以确保在控制和预防这种疾病的各种选择上做出明智的决策。
