Alesi Erin R, del Fabbro Egidio
From the Division of Hematology, Oncology and Palliative Care, Virginia Commonwealth University, Richmond, VA.
Cancer J. 2014 Sep-Oct;20(5):325-9. doi: 10.1097/PPO.0000000000000065.
Cancer patients experience multiple symptoms throughout their illness trajectory. Symptoms consistently occurring together, known as symptom clusters, share common pathophysiologic mechanisms. Understanding and targeting such symptom clusters may allow for more effective and efficient use of treatments for a variety of symptoms. Fatigue-anorexia-cachexia is one of the most prevalent symptom clusters and significantly impairs quality of life. In this review, we explore the fatigue-anorexia-cachexia symptom cluster and focus on current and emerging therapies with an emphasis on pharmacologic management.
癌症患者在其疾病进程中会经历多种症状。始终同时出现的症状，即症状群，具有共同的病理生理机制。了解并针对此类症状群可能会使各种症状的治疗更加有效和高效。疲劳-厌食-恶病质是最常见的症状群之一，会显著损害生活质量。在本综述中，我们探讨疲劳-厌食-恶病质症状群，并重点关注当前和新出现的疗法，尤其强调药物治疗。
