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针对波多黎各登革热的诊断、治疗及报告方式进行的医生调查。

Physician survey to determine how dengue is diagnosed, treated and reported in puerto rico.

作者信息

Tomashek Kay M, Biggerstaff Brad J, Ramos Mary M, Pérez-Guerra Carmen L, Garcia Rivera Enid J, Sun Wellington

机构信息

Dengue Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.

Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America.

出版信息

PLoS Negl Trop Dis. 2014 Oct 9;8(10):e3192. doi: 10.1371/journal.pntd.0003192. eCollection 2014 Oct.

Abstract

Dengue is a major cause of morbidity in Puerto Rico and is well-known to its physicians. Early case identification and timely initiation of treatment for patients with severe dengue can reduce medical complications and mortality. To determine clinical management and reporting practices, and assess knowledge of dengue and its management, a survey was sent to 2,512 physicians with a medical license in Puerto Rico. Of the 2,313 physicians who received the survey, 817 (35%) completed the questionnaire. Of the respondents, 708 were currently practicing medicine; 138 were board certified (Group 1), 282 were board eligible (Group 2), and 288 had not finished residency (Group 3). Although respondents clinically diagnosed, on average, 12 cases of dengue in the preceding three months, 31% did not report any suspected cases to public health officials while about half (56%) reported all cases. Overall, 29% of respondents correctly identified early signs of shock and 48% identified severe abdominal pain and persistent vomiting as warning signs for severe dengue with the proportion of correct respondents highest in Group 1. Reportedly about sixty percent (57%) appropriately never give corticosteroids or prophylactic platelet transfusions to dengue patients. One third (30%) of respondents correctly identified administration of intravenous colloid solution as the best treatment option for dengue patients with refractory shock and elevated hematocrit after an initial trial of intravenous crystalloids, and nearly one half (46%) correctly identified administration of a blood transfusion as the best option for dengue patients with refractory shock and decreased hematocrit after a trial of intravenous crystalloids. Even though dengue has been endemic in Puerto Rico for nearly 4 decades, knowledge of dengue management is still limited, compliance with WHO treatment guidelines is suboptimal, and underreporting is significant. These findings were used to design a post graduate training course to improve the clinical management of dengue.

摘要

登革热是波多黎各发病的主要原因,当地医生对此熟知。对重症登革热患者进行早期病例识别并及时开始治疗,可减少医疗并发症和死亡率。为确定临床管理和报告做法,并评估对登革热及其管理的了解情况,向波多黎各2512名持有行医执照的医生发送了一份调查问卷。在收到调查问卷的2313名医生中,817名(35%)完成了问卷。在受访者中,708名目前正在行医;138名获得了专科医师委员会认证(第1组),282名符合专科医师委员会认证资格(第2组),288名尚未完成住院医师培训(第3组)。尽管受访者在前三个月平均临床诊断出12例登革热病例,但31%的人未向公共卫生官员报告任何疑似病例,而约一半(56%)的人报告了所有病例。总体而言,29%的受访者正确识别出休克的早期迹象,48%的人将严重腹痛和持续呕吐识别为重症登革热的警示信号,第1组中正确回答的受访者比例最高。据报告,约60%(57%)的人从未给登革热患者使用过皮质类固醇或预防性血小板输注。三分之一(30%)的受访者正确识别出静脉输注胶体溶液是初次静脉输注晶体液后出现难治性休克且血细胞比容升高的登革热患者的最佳治疗选择,近一半(46%)的人正确识别出血液输注是初次静脉输注晶体液后出现难治性休克且血细胞比容降低的登革热患者的最佳选择。尽管登革热在波多黎各已流行近40年,但对登革热管理的了解仍然有限,对世界卫生组织治疗指南的依从性欠佳,且漏报情况严重。这些研究结果被用于设计一门研究生培训课程,以改善登革热的临床管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f864/4191957/1af74da00d23/pntd.0003192.g001.jpg

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