德国和英国规定的阿片类药物使用者的临床特征及治疗模式描述。
A description of clinical characteristics and treatment patterns observed within prescribed opioid users in Germany and the UK.
作者信息
Chevalier Pierre, Smulders Maartje, Chavoshi Soheil, Sostek Mark, LoCasale Robert
机构信息
IMS Health IMS HEALTH®, Medialaan 38, 1800 Vilvoorde, Belgium.
出版信息
Pain Manag. 2014 Jul;4(4):267-76. doi: 10.2217/pmt.14.26.
AIMS
To describe a cohort of new opioid users (adult noncancer patients) in terms of clinical characteristics and treatment patterns in the UK and Germany.
MATERIAL & METHODS: Data used were extracted from electronic medical records databases (UK: Clinical Practice Research Database-Hospital Episode Statistics; Germany: IMS Disease Analyzer) covering the 2008-2012 period.
RESULTS
Most eligible patients were treated with opioids for less than 6 months (UK: 78.7% and Germany: 93.7%) and indexed on weak opioids (UK: 89.5% and Germany: 88.6%). Most prescribed opioids were codeine (UK) and tramadol (Germany). Most prevalent comorbidities were dorsalgia/depression. Constipation was observed in 16.8%/17.4% (UK/Germany) of chronic users (>6 months).
CONCLUSION
While both populations were highly morbid populations largely initiated on weak opioids, chronic use was less common in Germany.
目的
描述英国和德国新使用阿片类药物的人群（成年非癌症患者）的临床特征和治疗模式。
材料与方法
使用的数据来自电子病历数据库（英国：临床实践研究数据库 - 医院事件统计；德国：IMS疾病分析器），涵盖2008 - 2012年期间。
结果
大多数符合条件的患者使用阿片类药物治疗少于6个月（英国：78.7%，德国：93.7%），且以弱阿片类药物为索引（英国：89.5%，德国：88.6%）。最常开具的阿片类药物是可待因（英国）和曲马多（德国）。最常见的合并症是背痛/抑郁症。在16.8%/17.4%（英国/德国）的长期使用者（>6个月）中观察到便秘。
结论
虽然这两个人群都是主要开始使用弱阿片类药物的高发病群体，但德国的长期使用情况较少见。
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