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[早产双胞胎:临床比较,辅助生殖技术与自然受孕]

[Premature twins: clinic comparison, reproductive assisted techniques versus spontaneous conception].

作者信息

Noriega-Alvarez Roxana, Iglesias-Leboreiro José, Bernardez-Zapata Isabel

机构信息

Servicio de Neonatología, División de Pediatría, Hospital Español de México, Distrito Federal, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2014 Sep-Oct;52(5):544-9.

Abstract

BACKGROUND

Twin pregnancies occur one out of every 800. Due to the increase in maternal age and infertility, the use of assisted reproductive technology (ART) has risen. Thirty five percent of pregnancies solved using ART are twin pregnancies. A RT consists of infertility treatments in which oocytes and sperm are manipulated. The objective of this study was to compare the clinical behavior of premature twins born through ART versus those born after spontaneous conception (SC).

METHODS

Retrolective cohort study. The data was obtained from the records of preterm twins born between August 2010 and August 2013. Preterm twins were categorized in two groups: the ones conceived using ART versus those conceived through SC. Demographic characteristics and neonatal outcomes were compared.

RESULTS

The total was of 398 patients: 208 conceived in consequence of ART and 190 through SC. The primary outcome and neonatal morbidities showed no significant difference, only the incidence of necrotizing enterocolitis and the use of parenteral nutrition showed significant difference. The length of hospital stay between groups was similar.

CONCLUSIONS

In our population of preterm twins, the mode of conception had no detectable effect on mortality or short term morbidities.

摘要

背景

双胎妊娠每800例中出现1例。由于产妇年龄增加和不孕不育问题,辅助生殖技术(ART)的使用有所上升。通过ART解决的妊娠中有35%是双胎妊娠。ART包括对卵母细胞和精子进行操作的不孕不育治疗。本研究的目的是比较通过ART出生的早产双胎与自然受孕(SC)出生的早产双胎的临床情况。

方法

回顾性队列研究。数据来自2010年8月至2013年8月出生的早产双胎记录。早产双胎分为两组:通过ART受孕的双胎和通过SC受孕的双胎。比较人口统计学特征和新生儿结局。

结果

共有398例患者:208例通过ART受孕,190例通过SC受孕。主要结局和新生儿发病率无显著差异,仅坏死性小肠结肠炎的发生率和肠外营养的使用有显著差异。两组之间的住院时间相似。

结论

在我们的早产双胎人群中,受孕方式对死亡率或短期发病率没有可检测到的影响。

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