在英国和爱尔兰，出现急性严重哮鸣的儿童会使用哪些静脉支气管扩张剂？
Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?
机构信息
Department of General Paediatrics, Children's Hospital for Wales, Cardiff, UK.
Paediatric Emergency Department, Bristol Royal Hospital for Children, Bristol, UK Academic Department of Emergency Care, University of the West of England, Bristol, UK.
出版信息
Thorax. 2015 Jan;70(1):88-91. doi: 10.1136/thoraxjnl-2014-206041. Epub 2014 Oct 10.
During a prospective 10-week assessment period, 3238 children aged 1-16 years presented with acute wheeze to Paediatric Emergency Research in the UK and Ireland centres. 110 (3.3%) received intravenous bronchodilators. Intravenous magnesium sulfate (MgSO4) was used in 67 (60.9%), salbutamol in 61 (55.5%) and aminophylline in 52 (47.3%) of cases. In 35 cases (31.8%), two drugs were used together, and in 18 cases (16.4%), all three drugs were administered. When used sequentially the most common order was salbutamol, then MgSO4, then aminophylline. Overall, 30 different intravenous treatment regimens were used varying in drugs, dose, rate and duration.
在一项为期 10 周的前瞻性评估期间，英国和爱尔兰儿科急救研究中心有 3238 名 1-16 岁的儿童因急性喘息就诊。110 名（3.3%）接受了静脉内支气管扩张剂治疗。在 67 例（60.9%）、61 例（55.5%）和 52 例（47.3%）患者中使用了静脉内硫酸镁（MgSO4）、沙丁胺醇和氨茶碱。在 35 例（31.8%）患者中，两种药物联合使用，在 18 例（16.4%）患者中，三种药物均被使用。当按顺序使用时，最常见的顺序是沙丁胺醇、硫酸镁、氨茶碱。总体而言，使用了 30 种不同的静脉内治疗方案，药物、剂量、输注速度和持续时间均有差异。
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