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美国各地儿科急诊科哮喘急性加重的管理。

Management of asthma exacerbations in pediatric emergency departments across the United States.

作者信息

Tanverdi Melisa S, Zaniletti Isabella, Navanandan Nidhya, Hardee Isabel, Liu Andrew H, Mistry Rakesh D

机构信息

Department of Pediatrics, Section of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA.

Children's Hospital Association, Lenexa, KS, USA.

出版信息

J Asthma. 2025 Jun 4:1-5. doi: 10.1080/02770903.2025.2513056.

Abstract

OBJECTIVES

There are 750,000 emergency department (ED) visits by children for asthma exacerbations in the United States annually. Despite changing evidence and epidemiology, there have not been recent assessments of acute asthma prevalence, management, and outcomes from pediatric EDs. This 40-center retrospective evaluation utilizes the Pediatric Hospital Information System to characterize pediatric ED asthma presentations from 2015-2020.

STUDY DESIGN

Children 2-18 years with asthma ICD-9/10 code and receipt of albuterol were included. Demographics, Child Opportunity Index (COI), ED management, return visits, and adjusted costs were evaluated. Data were summarized using standard descriptive statistics and trends assessed using Mann-Kendall trend test.

RESULTS

There were 414,264 encounters made by 256,209 unique patients; 21% had >1 visit in 12 months. Median age was 6 years, 61.6% male, 44.5% Black, and 68.5% publicly insured; 58.3% of visits were by patients with very low/low COI. Systemic corticosteroids were administered in 86.3% of visits; 52.7% used dexamethasone. Chest radiographs were obtained in 23% of encounters. Most (74.9%) encounters resulted in ED discharge with a downward trend of visits for exacerbations per 1,000 ED visits of -9.77, 95% CI [-9.99,-9.54], increase in disposition to intensive care unit of 2.01 [1.87,2.41] and decrease in home/other of -3.77 [-4.34,-3.20]. There was no significant trend in return visits. Total adjusted costs were ∼$900 million.

CONCLUSIONS

ED visits for asthma remain frequent and disproportionately affect children with lower social determinants of health. Dexamethasone has not been widely adopted as corticosteroid of choice and use of ancillary testing continues, highlighting opportunities for improvement in asthma care.

摘要

目的

在美国,每年有75万名儿童因哮喘急性发作前往急诊科就诊。尽管证据和流行病学情况不断变化,但近期尚未对儿科急诊科急性哮喘的患病率、管理及治疗结果进行评估。这项40中心的回顾性评估利用儿科医院信息系统对2015年至2020年儿科急诊科哮喘病例的情况进行描述。

研究设计

纳入患有哮喘且有ICD - 9/10编码并接受沙丁胺醇治疗的2至18岁儿童。对人口统计学、儿童机会指数(COI)、急诊科管理、复诊情况及调整后的费用进行评估。数据采用标准描述性统计进行汇总,并使用曼 - 肯德尔趋势检验评估趋势。

结果

256,209名不同患者共就诊414,264次;21%的患者在12个月内就诊超过1次。中位年龄为6岁,男性占61.6%,黑人占44.5%,公共保险覆盖者占68.5%;58.3%的就诊患者COI极低/低。86.3%的就诊患者接受了全身糖皮质激素治疗;52.7%使用了地塞米松。23%的就诊患者进行了胸部X光检查。大多数(74.9%)就诊患者在急诊科出院,每1000次急诊科就诊中哮喘急性发作就诊次数呈下降趋势,下降幅度为-9.77,95%置信区间[-9.99, -9.54],入住重症监护病房的比例增加2.01 [1.87, 2.41],回家/其他处置的比例下降-3.77 [-4.34, -3.20]。复诊情况无显著趋势。调整后的总费用约为9亿美元。

结论

哮喘患者前往急诊科就诊的情况仍然频繁,且对健康社会决定因素较低的儿童影响尤为严重。地塞米松尚未被广泛用作首选糖皮质激素,辅助检查仍在使用,这突出了哮喘治疗方面有待改进的机会。

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