Howard J, Hudspeth A J, Vale R D
Department of Physiology, University of California School of Medicine, San Francisco.
Nature. 1989 Nov 9;342(6246):154-8. doi: 10.1038/342154a0.
Kinesin is a motor protein that uses energy derived from ATP hydrolysis to move organelles along microtubules. Using a new technique for measuring the movement produced in vitro by individual kinesin molecules, it is shown that a single kinesin molecule can move a microtubule for several micrometers. New information about the mechanism of force generation by kinesin is presented.
驱动蛋白是一种马达蛋白,它利用ATP水解产生的能量沿着微管移动细胞器。通过一种测量单个驱动蛋白分子在体外产生运动的新技术,研究表明单个驱动蛋白分子能使微管移动数微米。文中还给出了关于驱动蛋白产生力的机制的新信息。