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水平半规管良性阵发性位置性眩晕的自然病程确实很短。

Natural history of horizontal canal benign paroxysmal positional vertigo is truly short.

作者信息

Shim Dae Bo, Ko Kyung Min, Lee Joon Hee, Park Hong Ju, Song Mee Hyun

机构信息

Department of Otorhinolaryngology, Myongji Hospital, 697-24 Hwajung-dong, Deokyang-gu, Goyang, Gyeonggi, 412-270, Korea.

出版信息

J Neurol. 2015 Jan;262(1):74-80. doi: 10.1007/s00415-014-7519-0. Epub 2014 Oct 11.

Abstract

The objective of the study is to characterize the natural course of positional vertigo and nystagmus in patients with horizontal canal benign paroxysmal positional vertigo (h-BPPV) and to analyze the difference in the natural course between the two variants of h-BPPV. We conducted a prospective study in 106 patients with geotropic type h-BPPV [h-BPPV (Geo)] (n = 43) and apogeotropic type h-BPPV [h-BPPV (Apo)] (n = 63) who agreed and signed the written informed consent of no treatment. All patients were asked to answer a detailed interview about the onset time of positional vertigo and to visit the hospital every 1-3 days. At every visit, they were interviewed about cessation time of positional vertigo and positional nystagmus was assessed. The mean period ± SD between the onset and remission of vertigo in the h-BPPV (Geo) was 6.7 ± 6.3 days, whereas that in the h-BPPV (Apo) was 3.7 ± 4.1 days. In addition, the mean period ± SD from the initial diagnosis to the disappearance of positional nystagmus in the h-BPPV (Geo) was 4.7 ± 3.9 days, whereas that in the h-BPPV (Apo) was 4.4 ± 5.0 days. Although the duration until natural remission of positional nystagmus did not differ between the two variants of h-BPPV, the remission of vertigo occurred faster in h-BPPV (Apo) than h-BPPV (Geo) (p < 0.05). The natural course of h-BPPV is much shorter than that indicated in previous reports. The positional vertigo disappeared faster in the h-BPPV (Apo) compared to the h-BPPV (Geo) unlike the positional nystagmus.

摘要

本研究的目的是描述水平半规管良性阵发性位置性眩晕(h-BPPV)患者位置性眩晕和眼球震颤的自然病程,并分析h-BPPV两种类型之间自然病程的差异。我们对106例同意并签署不进行治疗书面知情同意书的地向性h-BPPV [h-BPPV(Geo)](n = 43)和背地性h-BPPV [h-BPPV(Apo)](n = 63)患者进行了一项前瞻性研究。所有患者均被要求回答关于位置性眩晕发作时间的详细访谈,并每1 - 3天到医院就诊一次。每次就诊时,询问他们位置性眩晕的停止时间,并评估位置性眼球震颤。h-BPPV(Geo)组眩晕发作与缓解之间的平均时间±标准差为6.7±6.3天,而h-BPPV(Apo)组为3.7±4.1天。此外,h-BPPV(Geo)组从初始诊断到位置性眼球震颤消失的平均时间±标准差为4.7±3.9天,而h-BPPV(Apo)组为4.4±5.0天。虽然h-BPPV两种类型之间位置性眼球震颤自然缓解的持续时间没有差异,但h-BPPV(Apo)组眩晕的缓解比h-BPPV(Geo)组更快(p < 0.05)。h-BPPV的自然病程比以前报告中指出的要短得多。与位置性眼球震颤不同,h-BPPV(Apo)组的位置性眩晕比h-BPPV(Geo)组消失得更快。

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