Shim Dae Bo, Ko Kyung Min, Lee Joon Hee, Park Hong Ju, Song Mee Hyun
Department of Otorhinolaryngology, Myongji Hospital, 697-24 Hwajung-dong, Deokyang-gu, Goyang, Gyeonggi, 412-270, Korea.
J Neurol. 2015 Jan;262(1):74-80. doi: 10.1007/s00415-014-7519-0. Epub 2014 Oct 11.
The objective of the study is to characterize the natural course of positional vertigo and nystagmus in patients with horizontal canal benign paroxysmal positional vertigo (h-BPPV) and to analyze the difference in the natural course between the two variants of h-BPPV. We conducted a prospective study in 106 patients with geotropic type h-BPPV [h-BPPV (Geo)] (n = 43) and apogeotropic type h-BPPV [h-BPPV (Apo)] (n = 63) who agreed and signed the written informed consent of no treatment. All patients were asked to answer a detailed interview about the onset time of positional vertigo and to visit the hospital every 1-3 days. At every visit, they were interviewed about cessation time of positional vertigo and positional nystagmus was assessed. The mean period ± SD between the onset and remission of vertigo in the h-BPPV (Geo) was 6.7 ± 6.3 days, whereas that in the h-BPPV (Apo) was 3.7 ± 4.1 days. In addition, the mean period ± SD from the initial diagnosis to the disappearance of positional nystagmus in the h-BPPV (Geo) was 4.7 ± 3.9 days, whereas that in the h-BPPV (Apo) was 4.4 ± 5.0 days. Although the duration until natural remission of positional nystagmus did not differ between the two variants of h-BPPV, the remission of vertigo occurred faster in h-BPPV (Apo) than h-BPPV (Geo) (p < 0.05). The natural course of h-BPPV is much shorter than that indicated in previous reports. The positional vertigo disappeared faster in the h-BPPV (Apo) compared to the h-BPPV (Geo) unlike the positional nystagmus.
本研究的目的是描述水平半规管良性阵发性位置性眩晕(h-BPPV)患者位置性眩晕和眼球震颤的自然病程,并分析h-BPPV两种类型之间自然病程的差异。我们对106例同意并签署不进行治疗书面知情同意书的地向性h-BPPV [h-BPPV(Geo)](n = 43)和背地性h-BPPV [h-BPPV(Apo)](n = 63)患者进行了一项前瞻性研究。所有患者均被要求回答关于位置性眩晕发作时间的详细访谈,并每1 - 3天到医院就诊一次。每次就诊时,询问他们位置性眩晕的停止时间,并评估位置性眼球震颤。h-BPPV(Geo)组眩晕发作与缓解之间的平均时间±标准差为6.7±6.3天,而h-BPPV(Apo)组为3.7±4.1天。此外,h-BPPV(Geo)组从初始诊断到位置性眼球震颤消失的平均时间±标准差为4.7±3.9天,而h-BPPV(Apo)组为4.4±5.0天。虽然h-BPPV两种类型之间位置性眼球震颤自然缓解的持续时间没有差异,但h-BPPV(Apo)组眩晕的缓解比h-BPPV(Geo)组更快(p < 0.05)。h-BPPV的自然病程比以前报告中指出的要短得多。与位置性眼球震颤不同,h-BPPV(Apo)组的位置性眩晕比h-BPPV(Geo)组消失得更快。