在产毒艰难梭菌PCR核糖体分型027极低流行率的环境中，将BD MAX艰难梭菌检测法与Xpert艰难梭菌检测法进行性能评估。
Performance assessment of the BD MAX Cdiff assay in comparison to Xpert C. difficile assay in a setting with very low prevalence of toxigenic Clostridium difficile PCR ribotype 027.
作者信息
Chiang Donald, Ng Sally, La My-Van, Jureen Roland, Lin Raymond T P, Teo Jeanette W P
机构信息
Department of Laboratory Medicine, Microbiology Unit, National University Hospital, Singapore 119074, Singapore.
National Public Health Laboratory, Ministry of Health, Singapore.
出版信息
Anaerobe. 2014 Dec;30:156-8. doi: 10.1016/j.anaerobe.2014.09.021. Epub 2014 Oct 7.
In a clinical setting with low prevalence of 'epidemic' PCR ribotype 027, the BD MAX Cdiff assay was found to be a suitable alternative to the Xpert C. difficile assay for the detection of toxigenic Clostridium difficile in samples which are reflex PCR tested after obtaining a discrepant immunoassay result. There was no significant difference between the sensitivities and specificities of both commercial molecular assays.
在“流行的”PCR核糖体分型027患病率较低的临床环境中，发现BD MAX艰难梭菌检测法是Xpert艰难梭菌检测法的合适替代方法，用于在免疫测定结果出现差异后进行反射PCR检测的样本中检测产毒艰难梭菌。两种商业分子检测法的敏感性和特异性之间没有显著差异。
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