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肛裂管理的最新进展。

Update on the management of anal fissure.

作者信息

Higuero T

机构信息

11, boulevard du Général-Leclerc, 06240 Beausoleil, France.

出版信息

J Visc Surg. 2015 Apr;152(2 Suppl):S37-43. doi: 10.1016/j.jviscsurg.2014.07.007. Epub 2014 Oct 8.

Abstract

Anal fissure is an ulceration of the anoderm in the anal canal. Its pathogenesis is due to multiple factors: mechanical trauma, sphincter spasm, and ischemia. Treatment must address these causative factors. While American and British scientific societies have published recommendations, there is no formal treatment consensus in France. Medical treatment is non-specific, aimed at softening the stool and facilitating regular bowel movements; this results in healing of almost 50% of acute anal fissures. The risk of recurrent fissure remains high if the causative factors persist. If non-specific medical treatment fails, specific medical treatment can be offered to reversibly decrease hypertonic sphincter spasm. Surgery remains the most effective long-term treatment and should be offered for cases of chronic or complicated anal fissure but also for acute anal fissure with severe pain or for recurrent fissure despite optimal medical treatment. Surgical treatment is based on two principles that may be combined: decreasing sphincter tone and excision of the anal fissure. Lateral internal sphincterotomy (LIS) is the best-evaluated technique and remains the gold standard in English-speaking countries. Since LIS is associated with some risk of irreversible anal incontinence, its use is controversial in France where fissurectomy combined with anoplasty is preferred. Other techniques have been described to reduce the risk of incontinence (calibrated sphincterotomy, sphincteroplasty). The technique of forcible uncalibrated anal dilatation is no longer recommended.

摘要

肛裂是肛管皮肤的溃疡。其发病机制是由多种因素引起的:机械性创伤、括约肌痉挛和局部缺血。治疗必须针对这些致病因素。虽然美国和英国的科学协会已经发布了相关建议,但法国尚无正式的治疗共识。药物治疗并无特异性,旨在软化大便并促进规律排便;这使得近50%的急性肛裂得以愈合。如果致病因素持续存在,肛裂复发的风险仍然很高。如果非特异性药物治疗失败,可以采用特异性药物治疗来可逆性地减轻高张性括约肌痉挛。手术仍然是最有效的长期治疗方法,适用于慢性或复杂性肛裂病例,也适用于疼痛严重的急性肛裂或尽管接受了最佳药物治疗仍复发的肛裂。手术治疗基于两个可联合应用的原则:降低括约肌张力和切除肛裂。侧方内括约肌切开术(LIS)是评估最佳的技术,在英语国家仍然是金标准。由于LIS存在一定的不可逆性肛门失禁风险,在法国其应用存在争议,在法国更倾向于采用肛裂切除术联合肛门成形术。已经描述了其他降低失禁风险的技术(校准括约肌切开术、括约肌成形术)。不再推荐强行非校准性肛门扩张术。

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