Martínez-Anda Jaime Jesus, Barges-Coll Juan, Ponce-Gomez Juan Antonio, Perez-Pena Nadia, Revuelta-Gutierrez Rogelio
Department of Neurological Surgery, National Institute of Neurology and Neurosurgery Manuel Velasco Suarez, Mexico City, Mexico.
J Neurol Surg A Cent Eur Neurosurg. 2015 Jan;76(1):39-45. doi: 10.1055/s-0033-1358608. Epub 2014 Oct 12.
Trigeminal neuralgia is one of the most common causes of facial pain with the highest incidence in individuals > 60 years old. Despite the proven efficacy and safety of microvascular decompression (MVD) for the treatment of trigeminal neuralgia, some physicians are reluctant to perform the procedure in elderly patients because of potential complications.
In the present study, we analyze the outcome of MVDs performed over a 10-year period in elderly patients and compare the results with those obtained in younger patients. A total of 32% of the patients were ≥ 65 years of age at the time of diagnosis. All of the patients were treated via a small retrosigmoidal approach because of reluctance for medical treatment. Overall, 87% of the patients exhibited microvascular compression of the fifth nerve in the root entry zone and were treated using MVD; the remainder of the patients were treated using a trigeminal root compression technique when a vessel was not compressing the fifth nerve.
After the procedure, 93% reported complete relief of pain with a recurrence rate of 10.8% over a mean time of 43 months. A total of 10% of the patients experienced severe complications related to the operation with no mortality.
MVD continues to be the procedure of choice for the treatment of trigeminal neuralgia in patients reluctant to medical treatment, including elderly patients because age is not a contraindication.
三叉神经痛是面部疼痛最常见的病因之一,在60岁以上人群中发病率最高。尽管微血管减压术(MVD)治疗三叉神经痛的疗效和安全性已得到证实,但由于存在潜在并发症,一些医生不愿对老年患者实施该手术。
在本研究中,我们分析了10年间老年患者微血管减压术的结果,并将结果与年轻患者的结果进行比较。共有32%的患者在诊断时年龄≥65岁。由于不愿接受药物治疗,所有患者均采用乙状窦后小切口入路进行治疗。总体而言,87%的患者在神经根入区出现第五神经微血管压迫,并接受了微血管减压术治疗;其余患者在血管未压迫第五神经时采用三叉神经根压迫技术治疗。
术后,93%的患者报告疼痛完全缓解,平均43个月的复发率为10.8%。共有10%的患者出现与手术相关的严重并发症,无死亡病例。
对于包括老年患者在内的不愿接受药物治疗的三叉神经痛患者,微血管减压术仍然是首选的治疗方法,因为年龄并非禁忌症。