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间歇性步行:对老年餐后低血压患者的一种潜在治疗方法。

Intermittent walking: a potential treatment for older people with postprandial hypotension.

作者信息

Nair Shailaja, Visvanathan Renuka, Gentilcore Diana

机构信息

Aged and Extended Care Services, The Queen Elizabeth Hospital, Central Adelaide Local Health Network, Adelaide, South Australia; Adelaide Geriatrics Training and Research with Aged Care (G-TRAC) Centre, School of Medicine, University of Adelaide, Adelaide, South Australia.

Aged and Extended Care Services, The Queen Elizabeth Hospital, Central Adelaide Local Health Network, Adelaide, South Australia; Adelaide Geriatrics Training and Research with Aged Care (G-TRAC) Centre, School of Medicine, University of Adelaide, Adelaide, South Australia.

出版信息

J Am Med Dir Assoc. 2015 Feb;16(2):160-4. doi: 10.1016/j.jamda.2014.08.013. Epub 2014 Oct 11.

DOI:10.1016/j.jamda.2014.08.013
PMID:25306290
Abstract

BACKGROUND

Exercise has been proposed as a possible treatment for postprandial hypotension (PPH), yet, its use has not been extensively investigated. This study aimed to determine the effects of intermittent walking on blood pressure (BP) and heart rate (HR) following ingestion of a glucose drink in older people with PPH.

METHODS

Thirteen persons with PPH were recruited and studied on 2 randomized days (control, intervention). On both study days, participants ingested 200 mL of water containing 50 g glucose, followed by ambulatory BP and HR monitoring 6 minutely for 60 minutes, then 15 minutely until 120 minutes. On the intervention day, participants walked at their usual pace for 30 m every 30 minutes for 120 minutes.

RESULTS

On the control day, significant falls in systolic blood pressure (SBP) (P < .005) and diastolic blood pressure (DBP) (P = .016) were demonstrated between t = 0-120 minutes. On the intervention day, over the same period, there was no significant fall in SBP (P = .520), however, DBP still fell significantly (P = .045). There was a statistically significant difference (P = .005) for the area under the curve for the change in SBP from baseline for the study days but not DBP (P = .716). There was no significant change in HR (control: P = .854; intervention, P = .168) nor between the area under the curve (P = .798) for the change in HR from baseline for the study days.

CONCLUSIONS

This study suggests that in older people with PPH, intermittent walking at a usual pace attenuates the fall in SBP after ingestion of a glucose drink.

摘要

背景

运动已被提议作为餐后低血压(PPH)的一种可能治疗方法,然而,其应用尚未得到广泛研究。本研究旨在确定间歇性步行对PPH老年患者饮用葡萄糖饮料后血压(BP)和心率(HR)的影响。

方法

招募了13名PPH患者,并在2个随机日(对照、干预)进行研究。在两个研究日,参与者均饮用200 mL含50 g葡萄糖的水,随后每6分钟进行一次动态血压和心率监测,持续60分钟,然后每15分钟监测一次,直至120分钟。在干预日,参与者每30分钟以平常步伐行走30米,持续120分钟。

结果

在对照日,t = 0 - 120分钟期间收缩压(SBP)显著下降(P <.005),舒张压(DBP)显著下降(P =.016)。在干预日,同一时期SBP无显著下降(P =.520),然而,DBP仍显著下降(P =.045)。研究日SBP从基线变化的曲线下面积存在统计学显著差异(P =.005),但DBP无差异(P =.716)。HR无显著变化(对照:P =.854;干预,P =.168),研究日HR从基线变化的曲线下面积之间也无显著差异(P =.798)。

结论

本研究表明,对于PPH老年患者,以平常步伐进行间歇性步行可减轻饮用葡萄糖饮料后SBP的下降。

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