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重度妊娠中毒症时子宫胎盘血流的血液流变学特征

[Blood rheological characteristics of uteroplacental blood flow in severe gestosis].

作者信息

Pavlova T V, Petrukhin V A, Sumin S A, Selivanova A V, Syrtseva I S

出版信息

Arkh Patol. 2014 May-Jun;76(3):37-40.

PMID:25306609
Abstract

OBJECTIVE

To investigate the clinical and morphological features of uteroplacental blood flow during pregnancy in severe gestosis.

SUBJECTS AND METHODS

One hundred and twenty-five patients with severe gestosis were examined. Scanning probe and electron microscopy with macro- and microelement analysis and transmission microscopy were used to study their placentas, umbilical cords, endometrium, myometrium, and maternal blood in severe gestosis.

RESULTS

It is shown that circulatory disorders in the structural components of the examined tissues and organs, as well as changes in cytoarchitectonics and red blood cell functional properties may be a component of the trigger of disseminated intravascular coagulation, followed by impaired maternal and fetal vital activity.

CONCLUSION

The investigation of the pathomorphological features of the microcirculatory bed in the mother-placenta-fetus system in gestosis has shown that possible methods of their correction should be further sought.

摘要

目的

探讨重度妊娠中毒症患者孕期子宫胎盘血流的临床及形态学特征。

对象与方法

对125例重度妊娠中毒症患者进行检查。采用扫描探针和电子显微镜,结合宏观和微量元素分析以及透射显微镜,研究其胎盘、脐带、子宫内膜、子宫肌层以及重度妊娠中毒症患者的母体血液。

结果

结果表明,所检查组织和器官的结构成分中的循环障碍,以及细胞结构和红细胞功能特性的变化,可能是弥散性血管内凝血触发因素的一部分,继而导致母体和胎儿生命活动受损。

结论

对妊娠中毒症患者母胎胎盘系统微循环床病理形态学特征的研究表明,应进一步寻找可能的纠正方法。

相似文献

1
[Blood rheological characteristics of uteroplacental blood flow in severe gestosis].重度妊娠中毒症时子宫胎盘血流的血液流变学特征
Arkh Patol. 2014 May-Jun;76(3):37-40.
2
[Functional morphology of maternal placental circulation in severe gestosis].[重度妊娠中毒症患者母体胎盘循环的功能形态学]
Arkh Patol. 2012 Nov-Dec;74(6):19-22.
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[The clinico-diagnostic importance of evaluating the blood flow in the mother-placenta-fetus system in EPH gestosis].[妊娠期高血压疾病中评估母-胎-胎盘系统血流的临床诊断重要性]
Akush Ginekol (Mosk). 1993(3):12-4.
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Pre-eclampsia and partial uterine denervation.子痫前期与部分子宫去神经支配
Med Hypotheses. 2005;64(3):449-54. doi: 10.1016/j.mehy.2004.08.027.
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[The hemodynamic characteristics of mother and fetus in EPH gestosis].[妊娠高血压综合征中母胎的血流动力学特征]
Akush Ginekol (Mosk). 1993(6):18-22.
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[The mother-placenta-fetus system in diffuse toxic goiter: Morphopathological aspects].[弥漫性毒性甲状腺肿中的母-胎盘-胎儿系统:形态病理学方面]
Arkh Patol. 2015 Sep-Oct;77(5):14-17. doi: 10.17116/patol201577514-17.
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[Pathomorphological changes in the uterine wall in gestosis].
Lik Sprava. 2002(7):36-40.
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[Impaired maternal and fetal hemodynamics in the pathogenesis of gestosis].[妊娠期高血压疾病发病机制中孕产妇及胎儿血流动力学受损]
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[The role placental factors in formation of perinatal pathology in gestosis of different severity].[胎盘因素在不同严重程度妊娠中毒症围产期病理形成中的作用]
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