Hawkins M, Hosker M, Marcus B H, Rosal M C, Braun B, Stanek E J, Markenson G, Chasan-Taber L
Division of Biostatistics and Epidemiology, Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA, USA.
Diabet Med. 2015 Jan;32(1):108-15. doi: 10.1111/dme.12601. Epub 2014 Oct 29.
To pilot the feasibility of a prenatal lifestyle intervention to modify physical activity and diet among pregnant overweight and obese Hispanic women, with the aim of reducing risk factors for gestational diabetes mellitus.
Women were randomized either to a lifestyle intervention (n = 33, 48.5%), consisting of a culturally and linguistically modified, motivationally targeted, individually tailored 6-month prenatal programme, or to standard care (n = 35, 51.5%). Bilingual and bicultural health educators encouraged women to achieve guidelines for physical activity, decrease saturated fat and increase dietary fibre. Outcomes included gestational weight gain, infant birth weight and biomarkers associated with insulin resistance.
Patient retention up to delivery was 97% in both study groups. The lifestyle intervention attenuated the pregnancy-associated decline in moderate-intensity physical activity, but differences between groups were not significant (mean ± se -23.4 ± 16.6 vs -27.0 ± 16.2 metabolic equivalent of task h/week; P = 0.88). Vigorous-intensity activity increased during the course of pregnancy in the lifestyle intervention group (mean ± se 1.6 ± 0.8 metabolic equivalent of task h/week) and declined in the standard care group (-0.8 ± 0.8 metabolic equivalent of task h/week; P = 0.04). The lifestyle intervention group also had slightly lower gestational weight gain and infant birth weights compared with the standard care group; however, these differences were not statistically significant. There were no statistically significant differences in biomarkers of insulin resistance between groups.
Findings suggest that a motivationally matched lifestyle intervention is feasible and may help attenuate pregnancy-related decreases in vigorous physical activity in a population of overweight and obese Hispanic women. The intervention protocol can readily be translated into clinical practice in underserved and minority populations.
试行一项产前生活方式干预措施,以改变超重及肥胖的西班牙裔孕妇的身体活动和饮食状况,从而降低妊娠期糖尿病的风险因素。
将女性随机分为两组,一组接受生活方式干预(n = 33,48.5%),该干预包括一项经过文化和语言调整、以动机为导向、个性化定制的6个月产前项目;另一组接受标准护理(n = 35,51.5%)。双语和双文化健康教育工作者鼓励女性达到身体活动指南要求,减少饱和脂肪摄入并增加膳食纤维摄入。结果包括孕期体重增加、婴儿出生体重以及与胰岛素抵抗相关的生物标志物。
两个研究组直至分娩时的患者保留率均为97%。生活方式干预减缓了与妊娠相关的中等强度身体活动的下降,但两组之间的差异不显著(均值±标准误 -23.4 ± 16.6 与 -27.0 ± 16.2 代谢当量任务小时/周;P = 0.88)。在生活方式干预组中,高强度活动在孕期有所增加(均值±标准误 1.6 ± 0.8 代谢当量任务小时/周),而在标准护理组中则有所下降(-0.8 ± 0.8 代谢当量任务小时/周;P = 0.04)。与标准护理组相比,生活方式干预组的孕期体重增加和婴儿出生体重也略低;然而,这些差异无统计学意义。两组之间胰岛素抵抗生物标志物无统计学显著差异。
研究结果表明,动机匹配的生活方式干预是可行的,可能有助于减缓超重及肥胖的西班牙裔女性群体中与妊娠相关的高强度身体活动的减少。该干预方案可轻易转化为服务不足和少数族裔人群的临床实践。