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[木兰科木莲属厚朴类药用植物的研究]

[Studies on the medicinal plants of Magnoliaceae tu-hou-po of Manglietia].

作者信息

Song W Z, Cui J F, Zhang G D

出版信息

Yao Xue Xue Bao. 1989;24(4):295-9.

PMID:2530753
Abstract

Data from a survey of the drug market and investigation of the original plant of "Tu-hou-po", after careful botanical examinations, showed that the drugs were derived from 5 species of the genus Manglietia of Magnoliaceae, viz. Manglietia chingii Dandy, M. insignis (Wall.) Bl., M. duclouxii Finet et Gagnep., M. yuyuanensis Law and M. szechuanica Hu. Comparisons of the main characteristics of the plants, Tu-hou-po and Hou-po crude drugs and chemical components showed that Manglietia is taxonomically the closest to Magnolia and contained similar components (tab 1-2 and fig 1). The results of HPLC analysis demonstrated that they contained magnolol, honokiol, magnocurine and salicifoline, in different quantities. However, no magnosprengerine was detected. Besides, it was also found that the percentage of magnolol and honokiol contents were higher, while that of magnocurine was lower in Hou-po. On the contrary, the content of magnocurine was higher, while that of magnolol and honokiol were lower in Tu-hou-po. Manglietia chingii (Tu-hou-po) is being used as the Chinese traditional drug "Hou-po" in the clinic in Guangxi. Therefore, M. chingii is noteworthily exploited as a new resource of Hou-po for further research.

摘要

一项关于药材市场的调查以及对“土厚朴”原植物的考察数据,经仔细的植物学鉴定表明,这些药材来源于木兰科木兰属的5个物种,即景烈木兰、滇缅木兰、多花含笑、凹叶木兰和四川木兰。对这些植物、土厚朴和厚朴药材及化学成分的主要特征进行比较后发现,含笑属在分类学上与木兰属最为接近,且含有相似的成分(表1 - 2和图1)。高效液相色谱分析结果表明,它们均含有厚朴酚、和厚朴酚、木兰箭毒碱和柳叶木兰碱,但含量不同。然而,未检测到厚朴辛弗林。此外,还发现厚朴中厚朴酚与和厚朴酚的含量百分比更高,而木兰箭毒碱的含量更低。相反,土厚朴中木兰箭毒碱的含量更高,而厚朴酚与和厚朴酚的含量更低。景烈木兰(土厚朴)在广西临床上被用作传统中药“厚朴”。因此,景烈木兰作为厚朴的一种新资源值得进一步开发研究。

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