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管理儿科癌症患者感染方面的挑战:低收入和中等收入国家国家基本药物清单不够完善。

Challenges in managing infections among pediatric cancer patients: Suboptimal national essential medicines lists for low and middle income countries.

作者信息

Kirby Jeannette, Ojha Rohit P, Johnson Kyle M, Bittner Elizabeth C, Caniza Miguela A

机构信息

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee.

Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee.

出版信息

Pediatr Blood Cancer. 2015 Feb;62(2):204-207. doi: 10.1002/pbc.25273. Epub 2014 Oct 12.

DOI:10.1002/pbc.25273
PMID:25307693
Abstract

Infection management for pediatric cancer patients may be compromised in low and middle income countries (LMICs) if key antimicrobials are not included in national essential medicines lists. We screened national essential medicines lists for 81 LMICs, and assessed the frequency and corresponding 95% confidence limits (CL) of countries that included the 15 International Society of Paediatric Oncology-recommended antimicrobial agents. Only 19% (95% CL: 11%, 28%) of countries included all recommended antimicrobials in their national essential medicines lists. The selection of antimicrobial agents for national essential medicines lists in LMICs warrants attention from a pediatric cancer perspective. Pediatr Blood Cancer 2015;62:204-207. © 2014 Wiley Periodicals, Inc.

摘要

在低收入和中等收入国家(LMICs),如果关键抗菌药物未被列入国家基本药物清单,那么儿科癌症患者的感染管理可能会受到影响。我们筛查了81个低收入和中等收入国家的国家基本药物清单,并评估了将15种国际儿科肿瘤学会推荐的抗菌药物纳入清单的国家的频率及相应的95%置信区间(CL)。只有19%(95%CL:11%,28%)的国家在其国家基本药物清单中纳入了所有推荐的抗菌药物。从儿科癌症的角度来看,低收入和中等收入国家国家基本药物清单中抗菌药物的选择值得关注。《儿科血液与癌症》2015年;62:204 - 207。©2014威利期刊公司。

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