Celestino Francesco, Verri Cristian, De Carlo Francesco, Di Stasi Savino Mauro
Urologic Oncology Unit, Policlinico Casilino, Rome.
Arch Ital Urol Androl. 2014 Sep 30;86(3):227-8. doi: 10.4081/aiua.2014.3.227.
Acquired Hemophilia A (AHA) is a rare bleeding diathesis characterized by the development of autoantibodies against factor VIII (FVIII). About half of the cases are idiopathic and the other half are associated with autoimmune diseases, postpartum problems, infections, inflammatory bowel disease, drugs, lymphoproliferative disorders or solid tumors . AHA is associated with malignancies in 7-15% of cases. We report a case of AHA in a 65 year old patient with prostatic carcinoma, who underwent retropubic radical prostatectomy (RP).
获得性血友病A(AHA)是一种罕见的出血性素质,其特征是产生针对凝血因子VIII(FVIII)的自身抗体。约一半的病例为特发性,另一半与自身免疫性疾病、产后问题、感染、炎症性肠病、药物、淋巴增殖性疾病或实体瘤有关。7%至15%的AHA病例与恶性肿瘤有关。我们报告一例65岁前列腺癌患者发生AHA的病例,该患者接受了耻骨后根治性前列腺切除术(RP)。