Azam Khalid, Batool Zainab, Malik Ayesha, Chaudhry Manahil, Abdullah Mohammad
Medicine, Combined Military Hospital Lahore Medical College and Institute of Dentistry, Lahore, PAK.
Medicine, Hameed Latif Hospital, Lahore, PAK.
Cureus. 2020 Dec 1;12(12):e11817. doi: 10.7759/cureus.11817.
Acquired hemophilia A (AHA) is a bleeding diathesis caused by the production of autoantibodies to factor VIII (FVIII). It manifests as an isolated deranged activated partial thromboplastin time (aPTT) indicating a defect in the intrinsic coagulation pathway. Herein, we report a case of a 26-year-old woman who presented with hemoperitoneum in the postpartum period following a lower segment Caesarean section (LSCS). AHA carries significant mortality if it remains undiagnosed, and early recognition and measures to eradicate the acquired inhibitors are the mainstays of its management.
获得性血友病A（AHA）是一种由针对凝血因子VIII（FVIII）产生自身抗体引起的出血性素质。其表现为孤立的活化部分凝血活酶时间（aPTT）异常，提示内源性凝血途径存在缺陷。在此，我们报告一例26岁女性病例，该患者在低位剖宫产术后产褥期出现腹腔积血。如果AHA未被诊断，会有显著的死亡率，早期识别和消除获得性抑制物的措施是其治疗的主要支柱。
