Department of Medicine I, University of Erlangen-Nuremberg, Erlangen, Germany; Ludwig Demling Endoscopy Center of Excellence, University Hospital Erlangen, Erlangen, Germany.
Dig Endosc. 2015 Jan;27(2):232-8. doi: 10.1111/den.12395. Epub 2014 Dec 1.
Optical biopsy techniques were recently introduced to luminal gastrointestinal endoscopy. These include confocal laser endomicroscopy, spectroscopic imaging techniques and endocytoscopy. Optical biopsy techniques allow on demand in vivo histology during ongoing endoscopy, thereby potentially accelerating clinical diagnosis and specific therapy. In the present review, we focus on endocytoscopy as one of the rapidly emerging optical biopsy techniques. We provide technical details of currently available endocytoscopy systems and give tips on their use in clinical practice. We also summarize applications of endocytoscopy for colorectal pathologies.
光学活检技术最近被引入腔道内胃肠内镜检查中。这些技术包括共聚焦激光内镜检查、光谱成像技术和内镜细胞学检查。光学活检技术允许在进行中的内镜检查过程中按需进行体内组织学检查，从而有可能加速临床诊断和特定治疗。在本综述中，我们重点介绍内镜细胞学检查作为一种快速发展的光学活检技术。我们提供了目前可用的内镜细胞学检查系统的技术细节，并就其在临床实践中的使用提供了一些技巧。我们还总结了内镜细胞学检查在结直肠疾病中的应用。
