下肢骨关节炎运动疗法：系统评价结合试验序贯分析和网络荟萃分析。
Exercise for lower limb osteoarthritis: systematic review incorporating trial sequential analysis and network meta-analysis.
机构信息
Arthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK Warwick Centre for Applied Health Research and Delivery (WCAHRD), Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL UK.
Arthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire ST5 5BG, UK.
出版信息
Br J Sports Med. 2014 Nov;48(21):1579. doi: 10.1136/bjsports-2014-5555rep.
STUDY QUESTION
Which types of exercise intervention are most effective in relieving pain and improving function in people with lower limb osteoarthritis?
SUMMARY ANSWER
As of 2002 sufficient evidence had accumulated to show significant benefit of exercise over no exercise. An approach combining exercises to increase strength, flexibility, and aerobic capacity is most likely to be effective for relieving pain and improving function.
WHAT IS KNOWN AND WHAT THIS PAPER ADDS
Current international guidelines recommend therapeutic exercise (land or water based) as "core" and effective management of osteoarthritis. Evidence from this first network meta-analysis, largely based on studies in knee osteoarthritis, indicates that an intervention combining strengthening exercises with flexibility and aerobic exercise is most likely to improve outcomes of pain and function. Further trials of exercise versus no exercise are unlikely to overturn this positive result.
研究问题
哪种类型的运动干预对缓解下肢骨关节炎患者的疼痛和改善功能最有效？
总结答案
截至 2002 年，已有足够的证据表明运动对缓解疼痛和改善功能的效果明显优于不运动。结合力量、柔韧性和有氧运动的练习方法最有可能有效缓解疼痛和改善功能。
已知和本文新增内容
目前国际指南建议将治疗性运动（陆地或水上运动）作为“核心”和骨关节炎的有效管理方法。这项首次网络荟萃分析的证据主要基于膝关节骨关节炎的研究，表明将力量练习与柔韧性和有氧运动相结合的干预措施最有可能改善疼痛和功能的结果。进一步的运动与不运动的试验不太可能推翻这一积极结果。
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