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[乙型肝炎病毒的免疫预防]

[Immune prophylaxis against hepatitis B virus].

作者信息

Westh H

出版信息

Ugeskr Laeger. 1989 Oct 23;151(43):2784-7.

PMID:2531485
Abstract

Hepatitis-B infections can be prevented by vaccination. Although a safe and efficacious plasma-derived vaccine has been available in Denmark since 1983, only approximately 7,000 persons have been vaccinated. This was among other things due to an unwarranted suspicion that the vaccine could harbour HIV. A new hepatitis B vaccine produced by a recombinant yeast cell is without this stigma and the vaccine is cheaper. It is now time for an assessment of hepatitis B vaccination of employees and intensification of vaccination programs for high-risk persons. Screening procedures, vaccination schedules, efficacy studies and follow up programs are reviewed. Prospectives for new hepatitis B vaccines are described.

摘要

乙肝感染可通过接种疫苗预防。自1983年以来,丹麦就有安全有效的血浆源性疫苗,但仅有约7000人接种了该疫苗。这在一定程度上是由于无端怀疑该疫苗可能携带艾滋病毒。一种由重组酵母细胞生产的新型乙肝疫苗没有这种污名,而且价格更便宜。现在是时候对员工进行乙肝疫苗接种评估,并加强针对高危人群的疫苗接种计划了。本文回顾了筛查程序、疫苗接种时间表、疗效研究和后续项目。还描述了新型乙肝疫苗的前景。

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