Nielsen Rikke Maria, Andersen Flemming, Salskov-Iversen Maria Luise
Det Sundhedsvidenskabelige Fakultet, Syddansk Universitet, Winsløwsgade 19, 5000 Odense.
Ugeskr Laeger. 2014 Oct 13;176(42).
Marjolin's ulcer is an aggressive squamous cell carcinoma (SCC) found in chronically inflamed skin. SCC has been reported in smallpox vaccination sites, whereas basal cell carcinomas are more common in scar after bacille Calmette-Guérin (BCG) vaccination. A 72-year-old man presented with a chronic ulcer at the site of his childhood BCG vaccination. At the time of examination, a 3 × 1.5 cm fleshy and secreting ulcer was found on the shoulder. Biopsy revealed SCC, and the tumour was surgically removed. In conclusion, chronic ulcers, especially those originating in chronically inflamed skin, should be regularly biopsied to assure that malignant transformation has not occurred.
马乔林溃疡是一种发生于慢性炎症皮肤的侵袭性鳞状细胞癌（SCC）。SCC曾在天花疫苗接种部位被报道过，而卡介苗（BCG）接种后的瘢痕中基底细胞癌更为常见。一名72岁男性在其儿童时期卡介苗接种部位出现慢性溃疡。检查时，在肩部发现一个3×1.5厘米的肉质且有分泌物的溃疡。活检显示为SCC，肿瘤通过手术切除。总之，慢性溃疡，尤其是那些起源于慢性炎症皮肤的溃疡，应定期进行活检以确保未发生恶变。
