Hjira Naoufal, Frikh Rachid, ALBouzidi Abderrahmane, Boui Mohammed
Service de Dermatologie, Hôpital Militaire d'Instruction Mohamed V, Rabat, Maroc.
Service d'Anatomie pathologique, Hôpital Militaire d'Instruction Mohamed V, Rabat, Maroc.
Pan Afr Med J. 2014 Apr 14;17:280. doi: 10.11604/pamj.2014.17.280.2667. eCollection 2014.
Cerebral venous thrombosis (CVT) is a rare origin of stroke, the clinical presentation and etiologies vary. The prognosis is shown to be better compared to arterial thrombosis. Magnetic Resonance Imaging (MRI) and MR Venograpgy (MRV) are currently important tools for the diagnostic. We studied 30 cases of CVT diagnosed in the department of neurology of the University Hospital of Fez (Morocco). Patients diagnosed with CVT signs between January 2003 and October 2007 were included in the study. Cerebral CT-scan was performed in 27 cases (90%) while the MRI examination was done in 18 patients (67%); and most patients (90%) received anticoagulant therapy. The mean age of our patients was of 29 years (age range between 18 days and 65 years). A female predominance was observed (70%). The clinical presentation of patients was dominated by: headache in 24 cases (80%), motor and sensory disability in 15 cases (50%), seizures in 10 cases (33%) , consciousness disorder in 10 cases (33%). CVT was associated to post-partum in 10 cases (33%), infectious origin in 8 cases (26%), Behcet disease in 2 cases (7%), pulmonary carcinoma in 1 case, thrombocytemia in 1 case and idiopathic in 7 cases (23%). The evolution was good in 20 cases (67%), minor squelaes were observed in 6 patients (20%), while major squelaes was observed in 2 cases. Two cases of death were registered. The CVT is a pathology of good prognosis once the diagnosis is promptly established and early heparin treatment initiated.
脑静脉血栓形成（CVT）是一种罕见的中风病因，其临床表现和病因各不相同。与动脉血栓形成相比，其预后较好。磁共振成像（MRI）和磁共振静脉造影（MRV）是目前诊断的重要工具。我们研究了在非斯大学医院（摩洛哥）神经科诊断的30例CVT病例。2003年1月至2007年10月期间诊断出有CVT体征的患者被纳入研究。27例（90%）患者进行了脑部CT扫描，18例（67%）患者进行了MRI检查；大多数患者（90%）接受了抗凝治疗。我们患者的平均年龄为29岁（年龄范围在18天至65岁之间）。观察到女性占优势（70%）。患者的临床表现主要有：24例（80%）头痛，15例（50%）运动和感觉障碍，10例（33%）癫痫发作，10例（33%）意识障碍。CVT与产后有关的有10例（33%），感染性病因的有8例（26%），白塞病的有2例（7%），肺癌的有1例，血小板减少症的有1例，特发性的有7例（23%）。20例（67%）患者病情进展良好，6例（20%）患者有轻度后遗症，2例患者有重度后遗症。记录到2例死亡病例。一旦迅速确诊并尽早开始肝素治疗，CVT是一种预后良好的疾病。
