Torabipour Amin, Asl Zahra Ahmadi, Majdinasab Nastaran, Ghasemzadeh Roya, Tabesh Hamed, Arab Mohammad
Department of Health Economic and Management, School of Public Health, Tehran University of Medical Sciences Tehran, Iran.
Department of Rehabilitation Administration, School of Rehabilitation Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Int J Prev Med. 2014 Sep;5(9):1131-8.
Multiple sclerosis is a common and chronic neurologic disorder. This disorder imposes physical, economic, and psychosocial burden on individuals, their families and society. This study aims to analyze the costs of multiple sclerosis disease based on the severity of disability.
We performed a cross-sectional cost of illness study. This study was conducted in 332 patients of Khuzestan province of Iran. Data were included: Patient's characteristics, disability status, medical, and nonmedical costs and were gathered by using the questionnaire during 3 months period. Costs analysis was performed in the basis of expanded disability status scale (EDSS). Data were analyzed by using SPSS 18 software.
Mean age of the patients was 33.5 (standard deviation [SD]: 9.1) and 70.5% of patients were female. Mean EDSS score of the patients was 2.2 (SD: 1.6). Most patients (92.1%) had relapsing remitting multiple sclerosis (MS) form of the disease. Costs mean per patients was 8.6 ± 7.9 million Rial. The direct and indirect costs were 93.1% and 6.9% of total costs, respectively. The major cost of the disease belongs to the pharmaceutical treatment (22% of costs). The majority costs (approximately 62%) attributed to EDSS of 6-7 and >7. Furthermore, there was strong significant relationship between cost of illness and disability severity of patients (P < 0.05).
Cost mean per MS patients was relatively high. Furthermore, the results showed that cost of disease had positive and significant relationships with EDSS score that is, progression of disability increase costs of patients.
多发性硬化症是一种常见的慢性神经疾病。这种疾病给个人、其家庭和社会带来了身体、经济和心理社会负担。本研究旨在根据残疾严重程度分析多发性硬化症的疾病成本。
我们进行了一项横断面疾病成本研究。该研究在伊朗胡齐斯坦省的332名患者中进行。纳入的数据包括：患者特征、残疾状况、医疗和非医疗成本，并在3个月期间通过问卷调查收集。成本分析基于扩展残疾状态量表（EDSS）进行。数据使用SPSS 18软件进行分析。
患者的平均年龄为33.5岁（标准差[SD]：9.1），70.5%的患者为女性。患者的平均EDSS评分为2.2（SD：1.6）。大多数患者（92.1%）患有复发缓解型多发性硬化症（MS）。每位患者的平均成本为860万±790万里亚尔。直接成本和间接成本分别占总成本的93.1%和6.9%。该疾病的主要成本属于药物治疗（占成本的22%）。大多数成本（约62%）归因于EDSS评分为6 - 7和>7的患者。此外，疾病成本与患者的残疾严重程度之间存在强显著关系（P < 0.05）。
每位MS患者的平均成本相对较高。此外，结果表明疾病成本与EDSS评分呈正相关且具有显著关系，即残疾进展会增加患者成本。
