• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.

作者信息

Staudt Michelle R, Buro-Auriemma Lauren J, Walters Matthew S, Salit Jacqueline, Vincent Thomas, Shaykhiev Renat, Mezey Jason G, Tilley Ann E, Kaner Robert J, Ho Melisa W Y, Crystal Ronald G

机构信息

1 Weill Cornell Medical College New York, New York.

出版信息

Am J Respir Crit Care Med. 2014 Oct 15;190(8):955-8. doi: 10.1164/rccm.201406-1167LE.

DOI:10.1164/rccm.201406-1167LE
PMID:25317467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4299582/
Abstract
摘要

相似文献

1
Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.气道基底干细胞/祖细胞在慢性阻塞性肺疾病中再生气道上皮的能力减弱。
Am J Respir Crit Care Med. 2014 Oct 15;190(8):955-8. doi: 10.1164/rccm.201406-1167LE.
2
Early events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cells.慢性阻塞性肺疾病发病机制中的早期事件。吸烟诱导气道上皮基底祖细胞重编程。
Ann Am Thorac Soc. 2014 Dec;11 Suppl 5(Suppl 5):S252-8. doi: 10.1513/AnnalsATS.201402-049AW.
3
Airway epithelial stem cells and the pathophysiology of chronic obstructive pulmonary disease.气道上皮干细胞与慢性阻塞性肺疾病的病理生理学
Proc Am Thorac Soc. 2006 Nov;3(8):718-25. doi: 10.1513/pats.200605-117SF.
4
Airway basal cells. The "smoking gun" of chronic obstructive pulmonary disease.气道基底细胞。慢性阻塞性肺疾病的“确凿证据”。
Am J Respir Crit Care Med. 2014 Dec 15;190(12):1355-62. doi: 10.1164/rccm.201408-1492PP.
5
Smoking-induced CXCL14 expression in the human airway epithelium links chronic obstructive pulmonary disease to lung cancer.吸烟诱导人呼吸道上皮细胞中 CXCL14 的表达将慢性阻塞性肺疾病与肺癌联系起来。
Am J Respir Cell Mol Biol. 2013 Sep;49(3):418-25. doi: 10.1165/rcmb.2012-0396OC.
6
CLCA1 and TMEM16A: the link towards a potential cure for airway diseases.CLCA1和TMEM16A:通向气道疾病潜在治愈方法的纽带。
Expert Rev Respir Med. 2015 Oct;9(5):503-6. doi: 10.1586/17476348.2015.1081064. Epub 2015 Aug 20.
7
Airway epithelial cells: current concepts and challenges.气道上皮细胞:当前概念与挑战
Proc Am Thorac Soc. 2008 Sep 15;5(7):772-7. doi: 10.1513/pats.200805-041HR.
8
[Morphological changes in the respiratory organs in chronic obstructive pulmonary disease].[慢性阻塞性肺疾病呼吸器官的形态学变化]
Arkh Patol. 2016 Jan-Feb;78(1):42-50. doi: 10.17116/patol201678142-50.
9
Myb permits multilineage airway epithelial cell differentiation.Myb基因促进多谱系气道上皮细胞分化。
Stem Cells. 2014 Dec;32(12):3245-56. doi: 10.1002/stem.1814.
10
Airway epithelial repair, regeneration, and remodeling after injury in chronic obstructive pulmonary disease.慢性阻塞性肺疾病损伤后气道上皮的修复、再生和重塑
Proc Am Thorac Soc. 2006 Nov;3(8):726-33. doi: 10.1513/pats.200605-126SF.

引用本文的文献

1
Unflavored electronic cigarette exposure induces alterations in airway ciliary structure and function.无味电子烟暴露会引起气道纤毛结构和功能的改变。
Respir Res. 2025 Jul 2;26(1):223. doi: 10.1186/s12931-025-03302-w.
2
Role of Homeobox A1 in Airway Epithelial Generation from Human Airway Basal Cells.同源盒A1在人气道基底细胞生成气道上皮中的作用。
Cells. 2025 Apr 5;14(7):549. doi: 10.3390/cells14070549.
3
Compound screening in human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies.在人呼吸道基底细胞中进行化合物筛选,确定Wnt信号通路激活剂为潜在的促再生疗法。
J Cell Sci. 2025 Apr 1;138(7). doi: 10.1242/jcs.263487. Epub 2025 Apr 14.
4
Epithelialized chimeric repairing patch supports in situ healing of tracheal fistula.上皮化嵌合修复补片支持气管瘘原位愈合。
Sci Adv. 2025 Feb 14;11(7):eadt1320. doi: 10.1126/sciadv.adt1320.
5
Understanding the impact of ER stress on lung physiology.了解内质网应激对肺生理的影响。
Front Cell Dev Biol. 2024 Dec 18;12:1466997. doi: 10.3389/fcell.2024.1466997. eCollection 2024.
6
Autologous transplantation of P63 lung progenitor cells in patients with bronchiectasis: A randomized, single-blind, controlled trial.支气管扩张症患者中 P63 肺祖细胞的自体移植:一项随机、单盲、对照试验。
Cell Rep Med. 2024 Nov 19;5(11):101819. doi: 10.1016/j.xcrm.2024.101819.
7
Proteomic networks and related genetic variants associated with smoking and chronic obstructive pulmonary disease.与吸烟和慢性阻塞性肺疾病相关的蛋白质组学网络和相关遗传变异。
BMC Genomics. 2024 Sep 2;25(1):825. doi: 10.1186/s12864-024-10619-1.
8
Distinctive field effects of smoking and lung cancer case-control status on bronchial basal cell growth and signaling.吸烟和肺癌病例对照状态对支气管基底细胞生长和信号的独特影响。
Respir Res. 2024 Aug 19;25(1):317. doi: 10.1186/s12931-024-02924-w.
9
Multi-Tissue Integrated Tissue-Engineered Trachea Regeneration Based on 3D Printed Bioelastomer Scaffolds.基于 3D 打印生物弹性体支架的多组织整合组织工程气管再生。
Adv Sci (Weinh). 2024 Oct;11(39):e2405420. doi: 10.1002/advs.202405420. Epub 2024 Aug 19.
10
Extensive airway remodelling in severe COPD imparts resiliency to environmental stressors.严重慢性阻塞性肺疾病中广泛的气道重塑赋予了对环境应激源的弹性。
Thorax. 2024 May 20;79(6):491-492. doi: 10.1136/thorax-2024-221410.

本文引用的文献

1
Abnormalities in airway epithelial junction formation in chronic obstructive pulmonary disease.慢性阻塞性肺疾病中气道上皮连接形成异常。
Am J Respir Crit Care Med. 2014 Jun 1;189(11):1439-42. doi: 10.1164/rccm.201311-1982LE.
2
DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways.DNA 甲基化被广泛打乱,并与慢性阻塞性肺疾病小气道的表达变化有关。
Am J Respir Cell Mol Biol. 2014 May;50(5):912-22. doi: 10.1165/rcmb.2013-0304OC.
3
Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression.吸烟会导致小气道上皮的表观遗传变化,并相应地调节基因表达。
Hum Mol Genet. 2013 Dec 1;22(23):4726-38. doi: 10.1093/hmg/ddt326. Epub 2013 Jul 10.
4
Genomic impact of cigarette smoke, with application to three smoking-related diseases.香烟烟雾的基因组影响及其在三种与吸烟相关疾病中的应用。
Crit Rev Toxicol. 2012 Nov;42(10):877-89. doi: 10.3109/10408444.2012.725244. Epub 2012 Sep 18.
5
Pathophysiology of the small airways in chronic obstructive pulmonary disease.慢性阻塞性肺疾病小气道的病理生理学。
Respiration. 2012;84(2):89-97. doi: 10.1159/000341382. Epub 2012 Aug 6.
6
Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells.气道基底细胞血管内皮生长因子介导的串扰调节内皮细胞依赖性的人气道基底细胞生长支持。
Cell Mol Life Sci. 2012 Jul;69(13):2217-31. doi: 10.1007/s00018-012-0922-8. Epub 2012 Mar 1.
7
DNA methylation in stem cell renewal and multipotency.干细胞更新和多能性中的 DNA 甲基化。
Stem Cell Res Ther. 2011 Oct 31;2(5):42. doi: 10.1186/scrt83.
8
The human airway epithelial basal cell transcriptome.人类气道上皮基底细胞转录组。
PLoS One. 2011 May 4;6(5):e18378. doi: 10.1371/journal.pone.0018378.
9
Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo.吸烟使人体内气道上皮的顶端连接复合分子结构发生重塑。
Cell Mol Life Sci. 2011 Mar;68(5):877-92. doi: 10.1007/s00018-010-0500-x. Epub 2010 Sep 6.
10
Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling.气道基底干细胞:对其在上皮组织稳态和重塑中作用的展望。
Dis Model Mech. 2010 Sep-Oct;3(9-10):545-56. doi: 10.1242/dmm.006031. Epub 2010 Aug 10.