Nappi Rossella E, Pellegrinelli Alice, Campolo Federica, Lanzo Gabriele, Santamaria Valentina, Suragna Alessandro, Spinillo Arsenio, Benedetto Chiara
* Research Centre for Reproductive Medicine, Gynaecological Endocrinology and Menopause, Fondazione IRCCS San Matteo , Pavia , Italy.
Eur J Contracept Reprod Health Care. 2015 Feb;20(1):36-46. doi: 10.3109/13625187.2014.961598. Epub 2014 Oct 15.
We investigated levels of knowledge of the effects of combined hormonal contraceptives (CHCs) on general/reproductive health and physical/psychosexual wellbeing.
A cross-sectional study was conducted in two university hospitals in northern Italy. Healthy current-, past- and never CHC users (n = 545; age 18-44 years) completed a self-administered questionnaire.
Ninety-three percent of current-, 74% of past-, and 56% of never users believed they were sufficiently informed (χ(2): 67.1; p = 0.001) about the benefits and risks of CHCs. Respondents mentioned: (i) a reduced risk of ovarian (67%) and endometrial (53%) cancer; (ii) an increased risk of thrombosis (82%); (iii) an increased risk of breast cancer (45%); (iv) a decreased fertility (19%) and no influence on risk of sexually transmitted infections (48%); (v) a reduced risk of menstrual abnormalities (77%) and acne (79%); (vi) less dysmenorrhoea (83%) and more headache (56%), weight gain (74%), increased appetite (51%), leg cramps (77%), mood swings (45%), vaginal dryness (47%), and low sex drive (48%). Beliefs about diseases/conditions and symptoms were influenced by CHC use.
CHC use is linked to good knowledge of risks and benefits. Our data suggest HCPs must be proactive in providing relevant information so that women can choose their contraception with a balanced insight of side effects.
我们调查了复方激素避孕药（CHC）对一般/生殖健康以及身体/性心理健康影响的知识水平。
在意大利北部的两家大学医院进行了一项横断面研究。健康的当前、过去和从未使用过CHC的使用者（n = 545；年龄18 - 44岁）完成了一份自我管理的问卷。
93%的当前使用者、74%的过去使用者和56%的从未使用者认为他们已充分了解CHC的益处和风险（χ(2)：67.1；p = 0.001）。受访者提到：（i）卵巢癌（67%）和子宫内膜癌（53%）风险降低；（ii）血栓形成风险增加（82%）；（iii）乳腺癌风险增加（4%）；（iv）生育能力下降（19%）且对性传播感染风险无影响（48%）；（v）月经异常（77%）和痤疮（79%）风险降低；（vi）痛经减轻（83%），头痛增加（56%）、体重增加（74%）、食欲增加（51%）、腿部抽筋（77%）、情绪波动（45%）、阴道干燥（47%）和性欲低下（48%）。对疾病/状况和症状的认知受CHC使用情况影响。
使用CHC与对风险和益处的良好认知相关。我们的数据表明，医疗保健人员必须积极提供相关信息，以便女性在选择避孕方法时能全面了解副作用。
